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A Parallel Synthesis Approach to the Identification of Novel Diheteroarylamide-Based Compounds Blocking HIV Replication: Potential Inhibitors of HIV-1 Pre-mRNA Alternative Splicing.
Cheung PK, Horhant D, Bandy LE, Zamiri M, Rabea SM, Karagiosov SK, Matloobi M, McArthur S, Harrigan PR, Chabot B, Grierson DS. Cheung PK, et al. Among authors: grierson ds. J Med Chem. 2016 Mar 10;59(5):1869-79. doi: 10.1021/acs.jmedchem.5b01357. Epub 2016 Feb 29. J Med Chem. 2016. PMID: 26878150
The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation.
Dahal S, Cheng R, Cheung PK, Been T, Malty R, Geng M, Manianis S, Shkreta L, Jahanshahi S, Toutant J, Chan R, Park S, Brockman MA, Babu M, Mubareka S, Mossman K, Banerjee A, Gray-Owen S, Brown M, Houry WA, Chabot B, Grierson D, Cochrane A. Dahal S, et al. Viruses. 2021 Dec 30;14(1):60. doi: 10.3390/v14010060. Viruses. 2021. PMID: 35062264 Free PMC article.
A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.
Sohail M, Shkreta L, Toutant J, Rabea S, Babeu JP, Huard C, Coulombe-Huntington J, Delannoy A, Placet M, Geha S, Gendron FP, Boudreau F, Tyers M, Grierson DS, Chabot B. Sohail M, et al. Among authors: grierson ds. NAR Cancer. 2021 May 25;3(2):zcab019. doi: 10.1093/narcan/zcab019. eCollection 2021 Jun. NAR Cancer. 2021. PMID: 34316707 Free PMC article.
Development of Novel Monoamine Oxidase-B (MAO-B) Inhibitors with Reduced Blood-Brain Barrier Permeability for the Potential Management of Noncentral Nervous System (CNS) Diseases.
Gealageas R, Devineau A, So PPL, Kim CMJ, Surendradoss J, Buchwalder C, Heller M, Goebeler V, Dullaghan EM, Grierson DS, Putnins EE. Gealageas R, et al. Among authors: grierson ds. J Med Chem. 2018 Aug 23;61(16):7043-7064. doi: 10.1021/acs.jmedchem.7b01588. Epub 2018 Aug 1. J Med Chem. 2018. PMID: 30016860
91 results