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Cancer-associated DNA Hypermethylation of Polycomb Targets Requires DNMT3A Dual Recognition of Histone H2AK119 Ubiquitination and the Nucleosome Acidic Patch.
bioRxiv [Preprint]. 2024 Mar 20:2024.03.18.585588. doi: 10.1101/2024.03.18.585588.
bioRxiv. 2024.
PMID: 38562823
Free PMC article.
Preprint.
H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs.
Krug B, Hu B, Chen H, Ptack A, Chen X, Gretarsson KH, Deshmukh S, Kabir N, Andrade AF, Jabbour E, Harutyunyan AS, Lee JJY, Hulswit M, Faury D, Russo C, Xu X, Johnston MJ, Baguette A, Dahl NA, Weil AG, Ellezam B, Dali R, Blanchette M, Wilson K, Garcia BA, Soni RK, Gallo M, Taylor MD, Kleinman CL, Majewski J, Jabado N, Lu C.
Krug B, et al. Among authors: gretarsson kh.
bioRxiv [Preprint]. 2023 Nov 28:2023.11.28.567931. doi: 10.1101/2023.11.28.567931.
bioRxiv. 2023.
PMID: 38116029
Free PMC article.
Preprint.
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Dissecting the treatment-naive ecosystem of human melanoma brain metastasis.
Biermann J, Melms JC, Amin AD, Wang Y, Caprio LA, Karz A, Tagore S, Barrera I, Ibarra-Arellano MA, Andreatta M, Fullerton BT, Gretarsson KH, Sahu V, Mangipudy VS, Nguyen TTT, Nair A, Rogava M, Ho P, Koch PD, Banu M, Humala N, Mahajan A, Walsh ZH, Shah SB, Vaccaro DH, Caldwell B, Mu M, Wünnemann F, Chazotte M, Berhe S, Luoma AM, Driver J, Ingham M, Khan SA, Rapisuwon S, Slingluff CL Jr, Eigentler T, Röcken M, Carvajal R, Atkins MB, Davies MA, Agustinus A, Bakhoum SF, Azizi E, Siegelin M, Lu C, Carmona SJ, Hibshoosh H, Ribas A, Canoll P, Bruce JN, Bi WL, Agrawal P, Schapiro D, Hernando E, Macosko EZ, Chen F, Schwartz GK, Izar B.
Biermann J, et al. Among authors: gretarsson kh.
Cell. 2022 Jul 7;185(14):2591-2608.e30. doi: 10.1016/j.cell.2022.06.007.
Cell. 2022.
PMID: 35803246
Free PMC article.
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Cell Surface Mechanics Gate Embryonic Stem Cell Differentiation.
Bergert M, Lembo S, Sharma S, Russo L, Milovanović D, Gretarsson KH, Börmel M, Neveu PA, Hackett JA, Petsalaki E, Diz-Muñoz A.
Bergert M, et al. Among authors: gretarsson kh.
Cell Stem Cell. 2021 Feb 4;28(2):209-216.e4. doi: 10.1016/j.stem.2020.10.017. Epub 2020 Nov 17.
Cell Stem Cell. 2021.
PMID: 33207217
Free PMC article.
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Genome-Scale CRISPR Screening for Regulators of Cell Fate Transitions.
Carlini V, Gretarsson KH, Hackett JA.
Carlini V, et al. Among authors: gretarsson kh.
Methods Mol Biol. 2021;2214:91-108. doi: 10.1007/978-1-0716-0958-3_7.
Methods Mol Biol. 2021.
PMID: 32944905
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Dppa2 and Dppa4 counteract de novo methylation to establish a permissive epigenome for development.
Gretarsson KH, Hackett JA.
Gretarsson KH, et al.
Nat Struct Mol Biol. 2020 Aug;27(8):706-716. doi: 10.1038/s41594-020-0445-1. Epub 2020 Jun 22.
Nat Struct Mol Biol. 2020.
PMID: 32572256
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