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Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen.
Hekking KFW, Maroto S, van Kekem K, Haasjes FS, Slootweg JC, Oude Alink PGB, Dirks R, Sardana M, Bolster MG, Kuijpers B, Smith D, Doodeman R, Scheepstra M, Zech B, Mulvihill M, Renzetti LM, Babiss L, Centrella PA, Clark MA, Cuozzo JW, Guié MA, Sigel E, Habeshian S, Hupp CD, Liu J, Thomson HA, Zhang Y, Keefe AD, Müller G, Gremmen S. Hekking KFW, et al. Among authors: gremmen s. J Med Chem. 2024 Feb 22;67(4):3039-3065. doi: 10.1021/acs.jmedchem.3c02206. Epub 2024 Feb 2. J Med Chem. 2024. PMID: 38306405
The spread of the first introns in proto-eukaryotic paralogs.
Vosseberg J, Schinkel M, Gremmen S, Snel B. Vosseberg J, et al. Among authors: gremmen s. Commun Biol. 2022 May 19;5(1):476. doi: 10.1038/s42003-022-03426-5. Commun Biol. 2022. PMID: 35589959 Free PMC article.
Tryptophan metabolism and bacterial commensals prevent fungal dysbiosis in Arabidopsis roots.
Wolinska KW, Vannier N, Thiergart T, Pickel B, Gremmen S, Piasecka A, Piślewska-Bednarek M, Nakano RT, Belkhadir Y, Bednarek P, Hacquard S. Wolinska KW, et al. Among authors: gremmen s. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2111521118. doi: 10.1073/pnas.2111521118. Proc Natl Acad Sci U S A. 2021. PMID: 34853170 Free PMC article.