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4-Aryl-3-arylsulfonyl-quinolines as negative allosteric modulators of metabotropic GluR5 receptors: From HTS hit to development candidate.
Galambos J, Domány G, Nógrádi K, Wágner G, Keserű GM, Bobok A, Kolok S, Mikó-Bakk ML, Vastag M, Sághy K, Kóti J, Szakács Z, Béni Z, Gál K, Szombathelyi Z, Greiner I. Galambos J, et al. Among authors: greiner i. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1249-52. doi: 10.1016/j.bmcl.2016.01.024. Epub 2016 Jan 11. Bioorg Med Chem Lett. 2016. PMID: 26774652
Indole-2-carboxamidines as novel NR2B selective NMDA receptor antagonists.
Borza I, Kolok S, Ignácz-Szendrei G, Greiner I, Tárkányi G, Galgóczy K, Horváth C, Farkas S, Domány G. Borza I, et al. Among authors: greiner i. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5439-41. doi: 10.1016/j.bmcl.2005.08.110. Epub 2005 Oct 5. Bioorg Med Chem Lett. 2005. PMID: 16213709
Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists.
Borza I, Kolok S, Galgóczy K, Gere A, Horváth C, Farkas S, Greiner I, Domány G. Borza I, et al. Among authors: greiner i. Bioorg Med Chem Lett. 2007 Jan 15;17(2):406-9. doi: 10.1016/j.bmcl.2006.10.033. Epub 2006 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17074483
Selective NR1/2B N-methyl-D-aspartate receptor antagonists among indole-2-carboxamides and benzimidazole-2-carboxamides.
Borza I, Bozó E, Barta-Szalai G, Kiss C, Tárkányi G, Demeter A, Gáti T, Háda V, Kolok S, Gere A, Fodor L, Nagy J, Galgóczy K, Magdó I, Agai B, Fetter J, Bertha F, Keserü GM, Horváth C, Farkas S, Greiner I, Domány G. Borza I, et al. Among authors: greiner i. J Med Chem. 2007 Mar 8;50(5):901-14. doi: 10.1021/jm060420k. Epub 2007 Feb 10. J Med Chem. 2007. PMID: 17290978
Novel sulfonamides having dual dopamine D2 and D3 receptor affinity show in vivo antipsychotic efficacy with beneficial cognitive and EPS profile.
Agai-Csongor E, Nógrádi K, Galambos J, Vágó I, Bielik A, Magdó I, Ignácz-Szendrei G, Keseru GM, Greiner I, Laszlovszky I, Schmidt E, Kiss B, Sághy K, Laszy J, Gyertyán I, Zájer-Balázs M, Gémesi L, Domány G. Agai-Csongor E, et al. Among authors: greiner i. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5340-4. doi: 10.1016/j.bmcl.2007.08.015. Epub 2007 Aug 15. Bioorg Med Chem Lett. 2007. PMID: 17720494
54 results