Greig NH - Search Results

1

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.

Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktäschel P, Croteau DL, Akbari M, Greig NH, Fladby T, Nilsen H, Cader MZ, Mattson MP, Tavernarakis N, Bohr VA. Fang EF, et al. Among authors: greig nh. Nat Neurosci. 2019 Mar;22(3):401-412. doi: 10.1038/s41593-018-0332-9. Epub 2019 Feb 11. Nat Neurosci. 2019. PMID: 30742114 Free PMC article.

2

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

Culmsee C, Zhu X, Yu QS, Chan SL, Camandola S, Guo Z, Greig NH, Mattson MP. Culmsee C, et al. Among authors: greig nh. J Neurochem. 2001 Apr;77(1):220-8. doi: 10.1046/j.1471-4159.2001.t01-1-00220.x. J Neurochem. 2001. PMID: 11279278 Free article.

3

Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4.

Perry T, Haughey NJ, Mattson MP, Egan JM, Greig NH. Perry T, et al. Among authors: greig nh. J Pharmacol Exp Ther. 2002 Sep;302(3):881-8. doi: 10.1124/jpet.102.037481. J Pharmacol Exp Ther. 2002. PMID: 12183643

4

p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism.

Duan W, Zhu X, Ladenheim B, Yu QS, Guo Z, Oyler J, Cutler RG, Cadet JL, Greig NH, Mattson MP. Duan W, et al. Among authors: greig nh. Ann Neurol. 2002 Nov;52(5):597-606. doi: 10.1002/ana.10350. Ann Neurol. 2002. PMID: 12402257

5

Novel p53 inactivators with neuroprotective action: syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives.

Zhu X, Yu QS, Cutler RG, Culmsee CW, Holloway HW, Lahiri DK, Mattson MP, Greig NH. Zhu X, et al. Among authors: greig nh. J Med Chem. 2002 Nov 7;45(23):5090-7. doi: 10.1021/jm020044d. J Med Chem. 2002. PMID: 12408720

6

Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.

Perry T, Lahiri DK, Sambamurti K, Chen D, Mattson MP, Egan JM, Greig NH. Perry T, et al. Among authors: greig nh. J Neurosci Res. 2003 Jun 1;72(5):603-12. doi: 10.1002/jnr.10611. J Neurosci Res. 2003. PMID: 12749025

7

p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults.

Gilman CP, Chan SL, Guo Z, Zhu X, Greig N, Mattson MP. Gilman CP, et al. Neuromolecular Med. 2003;3(3):159-72. doi: 10.1385/NMM:3:3:159. Neuromolecular Med. 2003. PMID: 12835511

8

Learning from the gut.

Mattson MP, Perry T, Greig NH. Mattson MP, et al. Among authors: greig nh. Nat Med. 2003 Sep;9(9):1113-5. doi: 10.1038/nm0903-1113. Nat Med. 2003. PMID: 12949521 No abstract available.

9

New therapeutic strategies and drug candidates for neurodegenerative diseases: p53 and TNF-alpha inhibitors, and GLP-1 receptor agonists.

Greig NH, Mattson MP, Perry T, Chan SL, Giordano T, Sambamurti K, Rogers JT, Ovadia H, Lahiri DK. Greig NH, et al. Ann N Y Acad Sci. 2004 Dec;1035:290-315. doi: 10.1196/annals.1332.018. Ann N Y Acad Sci. 2004. PMID: 15681814 Review.

10

Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent.

Greig NH, Utsuki T, Ingram DK, Wang Y, Pepeu G, Scali C, Yu QS, Mamczarz J, Holloway HW, Giordano T, Chen D, Furukawa K, Sambamurti K, Brossi A, Lahiri DK. Greig NH, et al. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17213-8. doi: 10.1073/pnas.0508575102. Epub 2005 Nov 7. Proc Natl Acad Sci U S A. 2005. PMID: 16275899 Free PMC article.

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