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EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.
Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, Wu X, Stack EC, Loda M, Liu T, Xu H, Cato L, Thornton JE, Gregory RI, Morrissey C, Vessella RL, Montironi R, Magi-Galluzzi C, Kantoff PW, Balk SP, Liu XS, Brown M. Xu K, et al. Among authors: gregory ri. Science. 2012 Dec 14;338(6113):1465-9. doi: 10.1126/science.1227604. Science. 2012. PMID: 23239736 Free PMC article.
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.
Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, Iliopoulos D, Gregory RI. Piskounova E, et al. Among authors: gregory ri. Cell. 2011 Nov 23;147(5):1066-79. doi: 10.1016/j.cell.2011.10.039. Cell. 2011. PMID: 22118463 Free PMC article.
How does Lin28 let-7 control development and disease?
Thornton JE, Gregory RI. Thornton JE, et al. Among authors: gregory ri. Trends Cell Biol. 2012 Sep;22(9):474-82. doi: 10.1016/j.tcb.2012.06.001. Epub 2012 Jul 9. Trends Cell Biol. 2012. PMID: 22784697 Free PMC article. Review.
Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4).
Thornton JE, Du P, Jing L, Sjekloca L, Lin S, Grossi E, Sliz P, Zon LI, Gregory RI. Thornton JE, et al. Among authors: gregory ri. Nucleic Acids Res. 2014 Oct;42(18):11777-91. doi: 10.1093/nar/gku805. Epub 2014 Sep 15. Nucleic Acids Res. 2014. PMID: 25223788 Free PMC article.
Selective blockade of microRNA processing by Lin28.
Viswanathan SR, Daley GQ, Gregory RI. Viswanathan SR, et al. Among authors: gregory ri. Science. 2008 Apr 4;320(5872):97-100. doi: 10.1126/science.1154040. Epub 2008 Feb 21. Science. 2008. PMID: 18292307 Free PMC article.
The Lin28/let-7 axis regulates glucose metabolism.
Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI; DIAGRAM Consortium; MAGIC Investigators; Altshuler D, Daley GQ. Zhu H, et al. Among authors: gregory ri. Cell. 2011 Sep 30;147(1):81-94. doi: 10.1016/j.cell.2011.08.033. Cell. 2011. PMID: 21962509 Free PMC article.
miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction.
Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, Williams DA. Guda S, et al. Among authors: gregory ri. Mol Ther. 2015 Sep;23(9):1465-74. doi: 10.1038/mt.2015.113. Epub 2015 Jun 17. Mol Ther. 2015. PMID: 26080908 Free PMC article.
85 results