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Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells.
DiGiusto DL, Cannon PM, Holmes MC, Li L, Rao A, Wang J, Lee G, Gregory PD, Kim KA, Hayward SB, Meyer K, Exline C, Lopez E, Henley J, Gonzalez N, Bedell V, Stan R, Zaia JA. DiGiusto DL, et al. Among authors: gregory pd. Mol Ther Methods Clin Dev. 2016 Nov 9;3:16067. doi: 10.1038/mtm.2016.67. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27900346 Free PMC article.
Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases.
Li L, Krymskaya L, Wang J, Henley J, Rao A, Cao LF, Tran CA, Torres-Coronado M, Gardner A, Gonzalez N, Kim K, Liu PQ, Hofer U, Lopez E, Gregory PD, Liu Q, Holmes MC, Cannon PM, Zaia JA, DiGiusto DL. Li L, et al. Among authors: gregory pd. Mol Ther. 2013 Jun;21(6):1259-69. doi: 10.1038/mt.2013.65. Epub 2013 Apr 16. Mol Ther. 2013. PMID: 23587921 Free PMC article.
Efficient genome editing in hematopoietic stem cells with helper-dependent Ad5/35 vectors expressing site-specific endonucleases under microRNA regulation.
Saydaminova K, Ye X, Wang H, Richter M, Ho M, Chen H, Xu N, Kim JS, Papapetrou E, Holmes MC, Gregory PD, Palmer D, Ng P, Ehrhardt A, Lieber A. Saydaminova K, et al. Among authors: gregory pd. Mol Ther Methods Clin Dev. 2015 Jan 14;1:14057. doi: 10.1038/mtm.2014.57. eCollection 2015. Mol Ther Methods Clin Dev. 2015. PMID: 26052525 Free PMC article.
Genome editing with engineered zinc finger nucleases.
Urnov FD, Rebar EJ, Holmes MC, Zhang HS, Gregory PD. Urnov FD, et al. Among authors: gregory pd. Nat Rev Genet. 2010 Sep;11(9):636-46. doi: 10.1038/nrg2842. Nat Rev Genet. 2010. PMID: 20717154 Review.
133 results