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LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.
Wang X, Abraham S, McKenzie JAG, Jeffs N, Swire M, Tripathi VB, Luhmann UFO, Lange CAK, Zhai Z, Arthur HM, Bainbridge J, Moss SE, Greenwood J. Wang X, et al. Among authors: greenwood j. Nature. 2013 Jul 18;499(7458):306-11. doi: 10.1038/nature12345. Nature. 2013. PMID: 23868260 Free PMC article.
LRG1: an emerging player in disease pathogenesis.
Camilli C, Hoeh AE, De Rossi G, Moss SE, Greenwood J. Camilli C, et al. Among authors: greenwood j. J Biomed Sci. 2022 Jan 21;29(1):6. doi: 10.1186/s12929-022-00790-6. J Biomed Sci. 2022. PMID: 35062948 Free PMC article. Review.
Apelin is required for non-neovascular remodeling in the retina.
McKenzie JA, Fruttiger M, Abraham S, Lange CA, Stone J, Gandhi P, Wang X, Bainbridge J, Moss SE, Greenwood J. McKenzie JA, et al. Among authors: greenwood j. Am J Pathol. 2012 Jan;180(1):399-409. doi: 10.1016/j.ajpath.2011.09.035. Epub 2011 Nov 7. Am J Pathol. 2012. PMID: 22067912 Free PMC article.
The fetal mouse metatarsal bone explant as a model of angiogenesis.
Song W, Fhu CW, Ang KH, Liu CH, Johari NA, Lio D, Abraham S, Hong W, Moss SE, Greenwood J, Wang X. Song W, et al. Among authors: greenwood j. Nat Protoc. 2015 Oct;10(10):1459-73. doi: 10.1038/nprot.2015.097. Epub 2015 Sep 3. Nat Protoc. 2015. PMID: 26334866
LRG1 as a novel therapeutic target in eye disease.
De Rossi G, Da Vitoria Lobo ME, Greenwood J, Moss SE. De Rossi G, et al. Among authors: greenwood j. Eye (Lond). 2022 Feb;36(2):328-340. doi: 10.1038/s41433-021-01807-4. Epub 2022 Jan 5. Eye (Lond). 2022. PMID: 34987199 Free PMC article. Review.
Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis.
Singhal M, Gengenbacher N, Abdul Pari AA, Kamiyama M, Hai L, Kuhn BJ, Kallenberg DM, Kulkarni SR, Camilli C, Preuß SF, Leuchs B, Mogler C, Espinet E, Besemfelder E, Heide D, Heikenwalder M, Sprick MR, Trumpp A, Krijgsveld J, Schlesner M, Hu J, Moss SE, Greenwood J, Augustin HG. Singhal M, et al. Among authors: greenwood j. Sci Transl Med. 2021 Sep;13(609):eabe6805. doi: 10.1126/scitranslmed.abe6805. Epub 2021 Sep 1. Sci Transl Med. 2021. PMID: 34516824 Free PMC article.
Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway.
Dritsoula A, Dowsett L, Pilotti C, O'Connor MN, Moss SE, Greenwood J. Dritsoula A, et al. Among authors: greenwood j. Sci Rep. 2022 Mar 22;12(1):4867. doi: 10.1038/s41598-022-08516-2. Sci Rep. 2022. PMID: 35318338 Free PMC article.
In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations.
Kampik D, Basche M, Luhmann UFO, Nishiguchi KM, Williams JAE, Greenwood J, Moss SE, Han H, Azam S, Duran Y, Robbie SJ, Bainbridge JWB, Larkin DF, Smith AJ, Ali RR. Kampik D, et al. Among authors: greenwood j. Gene Ther. 2017 Dec;24(12):810-818. doi: 10.1038/gt.2017.89. Epub 2017 Nov 30. Gene Ther. 2017. PMID: 29188796
1,362 results