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p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).
Maor-Nof M, Shipony Z, Lopez-Gonzalez R, Nakayama L, Zhang YJ, Couthouis J, Blum JA, Castruita PA, Linares GR, Ruan K, Ramaswami G, Simon DJ, Nof A, Santana M, Han K, Sinnott-Armstrong N, Bassik MC, Geschwind DH, Tessier-Lavigne M, Attardi LD, Lloyd TE, Ichida JK, Gao FB, Greenleaf WJ, Yokoyama JS, Petrucelli L, Gitler AD. Maor-Nof M, et al. Among authors: greenleaf wj. Cell. 2021 Feb 4;184(3):689-708.e20. doi: 10.1016/j.cell.2020.12.025. Epub 2021 Jan 21. Cell. 2021. PMID: 33482083 Free PMC article.
Chromatin accessibility and the regulatory epigenome.
Klemm SL, Shipony Z, Greenleaf WJ. Klemm SL, et al. Among authors: greenleaf wj. Nat Rev Genet. 2019 Apr;20(4):207-220. doi: 10.1038/s41576-018-0089-8. Nat Rev Genet. 2019. PMID: 30675018 Review.
Chromatin accessibility dynamics in a model of human forebrain development.
Trevino AE, Sinnott-Armstrong N, Andersen J, Yoon SJ, Huber N, Pritchard JK, Chang HY, Greenleaf WJ, Pașca SP. Trevino AE, et al. Among authors: greenleaf wj. Science. 2020 Jan 24;367(6476):eaay1645. doi: 10.1126/science.aay1645. Science. 2020. PMID: 31974223 Free PMC article.
Long-range single-molecule mapping of chromatin accessibility in eukaryotes.
Shipony Z, Marinov GK, Swaffer MP, Sinnott-Armstrong NA, Skotheim JM, Kundaje A, Greenleaf WJ. Shipony Z, et al. Among authors: greenleaf wj. Nat Methods. 2020 Mar;17(3):319-327. doi: 10.1038/s41592-019-0730-2. Epub 2020 Feb 10. Nat Methods. 2020. PMID: 32042188 Free PMC article.
LKB1 inactivation modulates chromatin accessibility to drive metastatic progression.
Pierce SE, Granja JM, Corces MR, Brady JJ, Tsai MK, Pierce AB, Tang R, Chu P, Feldser DM, Chang HY, Bassik MC, Greenleaf WJ, Winslow MM. Pierce SE, et al. Among authors: greenleaf wj. Nat Cell Biol. 2021 Aug;23(8):915-924. doi: 10.1038/s41556-021-00728-4. Epub 2021 Aug 2. Nat Cell Biol. 2021. PMID: 34341533 Free PMC article.
176 results