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A phase I, placebo-controlled, randomized, double-blind, single ascending dose-ranging study to evaluate the safety and tolerability of a novel biophysical bronchodilator (S-1226) administered by nebulization in healthy volunteers.
Green FH, Leigh R, Fadayomi M, Lalli G, Chiu A, Shrestha G, ElShahat SG, Nelson DE, El Mays TY, Pieron CA, Dennis JH. Green FH, et al. Trials. 2016 Jul 28;17:361. doi: 10.1186/s13063-016-1489-8. Trials. 2016. PMID: 27464582 Free PMC article. Clinical Trial.
Myofibroblasts are increased in the lung parenchyma in asthma.
Boser SR, Mauad T, Araújo-Paulino BB, Mitchell I, Shrestha G, Chiu A, Butt J, Kelly MM, Caldini E, James A, Green FHY. Boser SR, et al. PLoS One. 2017 Aug 7;12(8):e0182378. doi: 10.1371/journal.pone.0182378. eCollection 2017. PLoS One. 2017. PMID: 28787016 Free PMC article.
193 results