Green AM - Search Results

1

Addressing the benefits of inhibiting APOBEC3-dependent mutagenesis in cancer.

Petljak M, Green AM, Maciejowski J, Weitzman MD. Petljak M, et al. Among authors: green am. Nat Genet. 2022 Nov;54(11):1599-1608. doi: 10.1038/s41588-022-01196-8. Epub 2022 Oct 24. Nat Genet. 2022. PMID: 36280735 Free PMC article. Review.

2

APOBEC3A damages the cellular genome during DNA replication.

Green AM, Landry S, Budagyan K, Avgousti DC, Shalhout S, Bhagwat AS, Weitzman MD. Green AM, et al. Cell Cycle. 2016;15(7):998-1008. doi: 10.1080/15384101.2016.1152426. Cell Cycle. 2016. PMID: 26918916 Free PMC article.

3

Cytosine Deaminase APOBEC3A Sensitizes Leukemia Cells to Inhibition of the DNA Replication Checkpoint.

Green AM, Budagyan K, Hayer KE, Reed MA, Savani MR, Wertheim GB, Weitzman MD. Green AM, et al. Cancer Res. 2017 Sep 1;77(17):4579-4588. doi: 10.1158/0008-5472.CAN-16-3394. Epub 2017 Jun 27. Cancer Res. 2017. PMID: 28655787 Free PMC article.

4

The spectrum of APOBEC3 activity: From anti-viral agents to anti-cancer opportunities.

Green AM, Weitzman MD. Green AM, et al. DNA Repair (Amst). 2019 Nov;83:102700. doi: 10.1016/j.dnarep.2019.102700. Epub 2019 Sep 13. DNA Repair (Amst). 2019. PMID: 31563041 Free PMC article. Review.

5

Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity.

Green AM, DeWeerd RA, O'Leary DR, Hansen AR, Hayer KE, Kulej K, Dineen AS, Szeto JH, Garcia BA, Weitzman MD. Green AM, et al. EMBO Rep. 2021 Sep 6;22(9):e52145. doi: 10.15252/embr.202052145. Epub 2021 Aug 4. EMBO Rep. 2021. PMID: 34347354 Free PMC article.

6

Qualitative and Quantitative Analysis of DNA Cytidine Deaminase Activity.

DeWeerd R, Green AM. DeWeerd R, et al. Among authors: green am. Methods Mol Biol. 2022;2444:161-169. doi: 10.1007/978-1-0716-2063-2_10. Methods Mol Biol. 2022. PMID: 35290637

7

Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers.

DeWeerd RA, Németh E, Póti Á, Petryk N, Chen CL, Hyrien O, Szüts D, Green AM. DeWeerd RA, et al. Among authors: green am. Cell Rep. 2022 Mar 22;38(12):110555. doi: 10.1016/j.celrep.2022.110555. Cell Rep. 2022. PMID: 35320711 Free PMC article.

8

Antigen glycosylation regulates efficacy of CAR T cells targeting CD19.

Heard A, Landmann JH, Hansen AR, Papadopolou A, Hsu YS, Selli ME, Warrington JM, Lattin J, Chang J, Ha H, Haug-Kroeper M, Doray B, Gill S, Ruella M, Hayer KE, Weitzman MD, Green AM, Fluhrer R, Singh N. Heard A, et al. Among authors: green am. Nat Commun. 2022 Jun 11;13(1):3367. doi: 10.1038/s41467-022-31035-7. Nat Commun. 2022. PMID: 35690611 Free PMC article.

9

The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress.

O'Leary DR, Hansen AR, Fingerman DF, Tran T, Harris BR, Hayer KE, Fan J, Chen E, Tennakoon M, DeWeerd RA, Meroni A, Szeto JH, Weitzman MD, Shalem O, Bednarski J, Vindigni A, Zhao X, Green AM. O'Leary DR, et al. Among authors: green am. bioRxiv [Preprint]. 2024 Mar 24:2023.11.28.568952. doi: 10.1101/2023.11.28.568952. bioRxiv. 2024. PMID: 38077016 Free PMC article. Preprint.

10

Controllable genome editing with split-engineered base editors.

Berríos KN, Evitt NH, DeWeerd RA, Ren D, Luo M, Barka A, Wang T, Bartman CR, Lan Y, Green AM, Shi J, Kohli RM. Berríos KN, et al. Among authors: green am. Nat Chem Biol. 2021 Dec;17(12):1262-1270. doi: 10.1038/s41589-021-00880-w. Epub 2021 Oct 18. Nat Chem Biol. 2021. PMID: 34663942 Free PMC article.

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