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Emergence of a multidrug-resistant and virulent Streptococcus pneumoniae lineage mediates serotype replacement after PCV13: an international whole-genome sequencing study.
Lo SW, Mellor K, Cohen R, Alonso AR, Belman S, Kumar N, Hawkins PA, Gladstone RA, von Gottberg A, Veeraraghavan B, Ravikumar KL, Kandasamy R, Pollard SAJ, Saha SK, Bigogo G, Antonio M, Kwambana-Adams B, Mirza S, Shakoor S, Nisar I, Cornick JE, Lehmann D, Ford RL, Sigauque B, Turner P, Moïsi J, Obaro SK, Dagan R, Diawara I, Skoczyńska A, Wang H, Carter PE, Klugman KP, Rodgers G, Breiman RF, McGee L, Bentley SD, Muñoz-Almagro C, Varon E; Global Pneumococcal Sequencing Consortium. Lo SW, et al. Lancet Microbe. 2022 Oct;3(10):e735-e743. doi: 10.1016/S2666-5247(22)00158-6. Epub 2022 Aug 16. Lancet Microbe. 2022. PMID: 35985351 Free PMC article.
A Streptococcus pneumoniae lineage usually associated with pneumococcal conjugate vaccine (PCV) serotypes is the most common cause of serotype 35B invasive disease in South Africa, following routine use of PCV.
Ndlangisa KM, du Plessis M, Lo S, de Gouveia L, Chaguza C, Antonio M, Kwambana-Adams B, Cornick J, Everett DB, Dagan R, Hawkins PA, Beall B, Corso A, Grassi Almeida SC, Ochoa TJ, Obaro S, Shakoor S, Donkor ES, Gladstone RA, Ho PL, Paragi M, Doiphode S, Srifuengfung S, Ford R, Moïsi J, Saha SK, Bigogo G, Sigauque B, Eser ÖK, Elmdaghri N, Titov L, Turner P, Kumar KLR, Kandasamy R, Egorova E, Ip M, Breiman RF, Klugman KP, McGee L, Bentley SD, von Gottberg A, The Global Pneumococcal Sequencing Consortium. Ndlangisa KM, et al. Among authors: grassi almeida sc. Microb Genom. 2022 Apr;8(4):000746. doi: 10.1099/mgen.0.000746. Microb Genom. 2022. PMID: 35384831 Free PMC article.
Putative novel cps loci in a large global collection of pneumococci.
van Tonder AJ, Gladstone RA, Lo SW, Nahm MH, du Plessis M, Cornick J, Kwambana-Adams B, Madhi SA, Hawkins PA, Benisty R, Dagan R, Everett D, Antonio M, Klugman KP, von Gottberg A, Breiman RF, McGee L, Bentley SD; The Global Pneumococcal Sequencing Consortium. van Tonder AJ, et al. Microb Genom. 2019 Jul;5(7):e000274. doi: 10.1099/mgen.0.000274. Epub 2019 Jun 11. Microb Genom. 2019. PMID: 31184299 Free PMC article.
Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.
Lo SW, Gladstone RA, van Tonder AJ, Lees JA, du Plessis M, Benisty R, Givon-Lavi N, Hawkins PA, Cornick JE, Kwambana-Adams B, Law PY, Ho PL, Antonio M, Everett DB, Dagan R, von Gottberg A, Klugman KP, McGee L, Breiman RF, Bentley SD; Global Pneumococcal Sequencing Consortium. Lo SW, et al. Lancet Infect Dis. 2019 Jul;19(7):759-769. doi: 10.1016/S1473-3099(19)30297-X. Epub 2019 Jun 10. Lancet Infect Dis. 2019. PMID: 31196809 Free PMC article.