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Synaptopathies: diseases of the synaptome.
Grant SG. Grant SG. Curr Opin Neurobiol. 2012 Jun;22(3):522-9. doi: 10.1016/j.conb.2012.02.002. Epub 2012 Mar 10. Curr Opin Neurobiol. 2012. PMID: 22409856 Review.
TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function.
Coba MP, Komiyama NH, Nithianantharajah J, Kopanitsa MV, Indersmitten T, Skene NG, Tuck EJ, Fricker DG, Elsegood KA, Stanford LE, Afinowi NO, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG. Coba MP, et al. Among authors: grant sg. J Neurosci. 2012 Oct 3;32(40):13987-99. doi: 10.1523/JNEUROSCI.2433-12.2012. J Neurosci. 2012. PMID: 23035106 Free PMC article.
Synaptic scaffold evolution generated components of vertebrate cognitive complexity.
Nithianantharajah J, Komiyama NH, McKechanie A, Johnstone M, Blackwood DH, St Clair D, Emes RD, van de Lagemaat LN, Saksida LM, Bussey TJ, Grant SG. Nithianantharajah J, et al. Among authors: grant sg. Nat Neurosci. 2013 Jan;16(1):16-24. doi: 10.1038/nn.3276. Epub 2012 Dec 2. Nat Neurosci. 2013. PMID: 23201973 Free PMC article.
Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence.
Fernández E, Collins MO, Frank RAW, Zhu F, Kopanitsa MV, Nithianantharajah J, Lemprière SA, Fricker D, Elsegood KA, McLaughlin CL, Croning MDR, Mclean C, Armstrong JD, Hill WD, Deary IJ, Cencelli G, Bagni C, Fromer M, Purcell SM, Pocklington AJ, Choudhary JS, Komiyama NH, Grant SGN. Fernández E, et al. Cell Rep. 2017 Oct 17;21(3):679-691. doi: 10.1016/j.celrep.2017.09.045. Cell Rep. 2017. PMID: 29045836 Free PMC article.
Learning and reaction times in mouse touchscreen tests are differentially impacted by mutations in genes encoding postsynaptic interacting proteins SYNGAP1, NLGN3, DLGAP1, DLGAP2 and SHANK2.
Horner AE, Norris RH, McLaren-Jones R, Alexander L, Komiyama NH, Grant SGN, Nithianantharajah J, Kopanitsa MV. Horner AE, et al. Genes Brain Behav. 2021 Jan;20(1):e12723. doi: 10.1111/gbb.12723. Epub 2020 Dec 29. Genes Brain Behav. 2021. PMID: 33347690 Free PMC article.
Gene targeting and synaptic plasticity.
Grant SG. Grant SG. Curr Opin Neurobiol. 1994 Oct;4(5):687-92. doi: 10.1016/0959-4388(94)90010-8. Curr Opin Neurobiol. 1994. PMID: 7849524 Review.
Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins.
Hill WD, Davies G, van de Lagemaat LN, Christoforou A, Marioni RE, Fernandes CP, Liewald DC, Croning MD, Payton A, Craig LC, Whalley LJ, Horan M, Ollier W, Hansell NK, Wright MJ, Martin NG, Montgomery GW, Steen VM, Le Hellard S, Espeseth T, Lundervold AJ, Reinvang I, Starr JM, Pendleton N, Grant SG, Bates TC, Deary IJ. Hill WD, et al. Among authors: grant sg. Transl Psychiatry. 2014 Jan 7;4(1):e341. doi: 10.1038/tp.2013.114. Transl Psychiatry. 2014. PMID: 24399044 Free PMC article.
280 results