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Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE-/- mouse model of atherosclerosis with alterations in IL10/AMPKα pathway.
Thompson D, Morrice N, Grant L, Le Sommer S, Ziegler K, Whitfield P, Mody N, Wilson HM, Delibegović M. Thompson D, et al. Among authors: grant l. Mol Metab. 2017 Jun 13;6(8):845-853. doi: 10.1016/j.molmet.2017.06.003. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752048 Free PMC article.
Myeloid-cell protein tyrosine phosphatase-1B deficiency in mice protects against high-fat diet and lipopolysaccharide-induced inflammation, hyperinsulinemia, and endotoxemia through an IL-10 STAT3-dependent mechanism.
Grant L, Shearer KD, Czopek A, Lees EK, Owen C, Agouni A, Workman J, Martin-Granados C, Forrester JV, Wilson HM, Mody N, Delibegovic M. Grant L, et al. Diabetes. 2014 Feb;63(2):456-70. doi: 10.2337/db13-0885. Epub 2013 Nov 1. Diabetes. 2014. PMID: 24186864
Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue.
Mcilroy GD, Tammireddy SR, Maskrey BH, Grant L, Doherty MK, Watson DG, Delibegović M, Whitfield PD, Mody N. Mcilroy GD, et al. Among authors: grant l. Biochem Pharmacol. 2016 Jan 15;100:86-97. doi: 10.1016/j.bcp.2015.11.017. Epub 2015 Nov 22. Biochem Pharmacol. 2016. PMID: 26592777 Free PMC article.
Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis.
Owen C, Czopek A, Agouni A, Grant L, Judson R, Lees EK, Mcilroy GD, Göransson O, Welch A, Bence KK, Kahn BB, Neel BG, Mody N, Delibegović M. Owen C, et al. Among authors: grant l. PLoS One. 2012;7(2):e32700. doi: 10.1371/journal.pone.0032700. Epub 2012 Feb 28. PLoS One. 2012. PMID: 22389718 Free PMC article.
Response to comment by Moxon et al.
Thompson D, Morrice N, Grant L, Le Sommer S, Lees EK, Mody N, Wilson HM, Delibegovic M. Thompson D, et al. Among authors: grant l. Clin Sci (Lond). 2018 Jan 2;132(1):39-41. doi: 10.1042/CS20171555. Print 2018 Jan 16. Clin Sci (Lond). 2018. PMID: 29295952 Free PMC article. No abstract available.
867 results