Grandis JR - Search Results

1

A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.

Swaney DL, Ramms DJ, Wang Z, Park J, Goto Y, Soucheray M, Bhola N, Kim K, Zheng F, Zeng Y, McGregor M, Herrington KA, O'Keefe R, Jin N, VanLandingham NK, Foussard H, Von Dollen J, Bouhaddou M, Jimenez-Morales D, Obernier K, Kreisberg JF, Kim M, Johnson DE, Jura N, Grandis JR, Gutkind JS, Ideker T, Krogan NJ. Swaney DL, et al. Among authors: grandis jr. Science. 2021 Oct;374(6563):eabf2911. doi: 10.1126/science.abf2911. Epub 2021 Oct 1. Science. 2021. PMID: 34591642 Free PMC article.

2

Bcl-2 but not Bax expression is associated with apoptosis in normal and transformed squamous epithelium.

Drenning SD, Marcovitch AJ, Johnson DE, Melhem MF, Tweardy DJ, Grandis JR. Drenning SD, et al. Among authors: grandis jr. Clin Cancer Res. 1998 Nov;4(11):2913-21. Clin Cancer Res. 1998. PMID: 9829760

3

Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells.

Miranda MB, Dyer KF, Grandis JR, Johnson DE. Miranda MB, et al. Among authors: grandis jr. Leukemia. 2003 Feb;17(2):390-400. doi: 10.1038/sj.leu.2402779. Leukemia. 2003. PMID: 12592339

4

Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth.

Leong PL, Andrews GA, Johnson DE, Dyer KF, Xi S, Mai JC, Robbins PD, Gadiparthi S, Burke NA, Watkins SF, Grandis JR. Leong PL, et al. Among authors: grandis jr. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4138-43. doi: 10.1073/pnas.0534764100. Epub 2003 Mar 14. Proc Natl Acad Sci U S A. 2003. PMID: 12640143 Free PMC article.

5

Responsiveness to the retinoic acid receptor-selective retinoid LGD1550 correlates with abrogation of transforming growth factor alpha/epidermal growth factor receptor autocrine signaling in head and neck squamous carcinoma cells.

Lango M, Wentzel AL, Song JI, Xi S, Johnson DE, Lamph WW, Miller L, Grandis JR. Lango M, et al. Among authors: grandis jr. Clin Cancer Res. 2003 Sep 15;9(11):4205-13. Clin Cancer Res. 2003. PMID: 14519647

6

Cross-talk between G protein-coupled receptor and epidermal growth factor receptor signaling pathways contributes to growth and invasion of head and neck squamous cell carcinoma.

Thomas SM, Bhola NE, Zhang Q, Contrucci SC, Wentzel AL, Freilino ML, Gooding WE, Siegfried JM, Chan DC, Grandis JR. Thomas SM, et al. Among authors: grandis jr. Cancer Res. 2006 Dec 15;66(24):11831-9. doi: 10.1158/0008-5472.CAN-06-2876. Cancer Res. 2006. PMID: 17178880

7

Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer.

Zhang Q, Bhola NE, Lui VW, Siwak DR, Thomas SM, Gubish CT, Siegfried JM, Mills GB, Shin D, Grandis JR. Zhang Q, et al. Among authors: grandis jr. Mol Cancer Ther. 2007 Apr;6(4):1414-24. doi: 10.1158/1535-7163.MCT-06-0678. Mol Cancer Ther. 2007. PMID: 17431120 Free article.

8

Targeting antiapoptotic Bcl-2 family members with cell-permeable BH3 peptides induces apoptosis signaling and death in head and neck squamous cell carcinoma cells.

Li R, Boehm AL, Miranda MB, Shangary S, Grandis JR, Johnson DE. Li R, et al. Among authors: grandis jr. Neoplasia. 2007 Oct;9(10):801-11. doi: 10.1593/neo.07394. Neoplasia. 2007. PMID: 17971900 Free PMC article.

9

Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer.

Bhola NE, Grandis JR. Bhola NE, et al. Among authors: grandis jr. Front Biosci. 2008 Jan 1;13:1857-65. doi: 10.2741/2805. Front Biosci. 2008. PMID: 17981673 Review.

10

Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.

Boehm AL, Sen M, Seethala R, Gooding WE, Freilino M, Wong SM, Wang S, Johnson DE, Grandis JR. Boehm AL, et al. Among authors: grandis jr. Mol Pharmacol. 2008 Jun;73(6):1632-42. doi: 10.1124/mol.107.044636. Epub 2008 Mar 6. Mol Pharmacol. 2008. PMID: 18326051 Free PMC article.

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