Grandis JR - Search Results

1

Targeting the IL-6/JAK/STAT3 signalling axis in cancer.

Johnson DE, O'Keefe RA, Grandis JR. Johnson DE, et al. Among authors: grandis jr. Nat Rev Clin Oncol. 2018 Apr;15(4):234-248. doi: 10.1038/nrclinonc.2018.8. Epub 2018 Feb 6. Nat Rev Clin Oncol. 2018. PMID: 29405201 Free PMC article. Review.

2

Bcl-2 but not Bax expression is associated with apoptosis in normal and transformed squamous epithelium.

Drenning SD, Marcovitch AJ, Johnson DE, Melhem MF, Tweardy DJ, Grandis JR. Drenning SD, et al. Among authors: grandis jr. Clin Cancer Res. 1998 Nov;4(11):2913-21. Clin Cancer Res. 1998. PMID: 9829760

3

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo.

Grandis JR, Drenning SD, Zeng Q, Watkins SC, Melhem MF, Endo S, Johnson DE, Huang L, He Y, Kim JD. Grandis JR, et al. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4227-32. doi: 10.1073/pnas.97.8.4227. Proc Natl Acad Sci U S A. 2000. PMID: 10760290 Free PMC article.

4

Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells.

Miranda MB, Dyer KF, Grandis JR, Johnson DE. Miranda MB, et al. Among authors: grandis jr. Leukemia. 2003 Feb;17(2):390-400. doi: 10.1038/sj.leu.2402779. Leukemia. 2003. PMID: 12592339

5

Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth.

Leong PL, Andrews GA, Johnson DE, Dyer KF, Xi S, Mai JC, Robbins PD, Gadiparthi S, Burke NA, Watkins SF, Grandis JR. Leong PL, et al. Among authors: grandis jr. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4138-43. doi: 10.1073/pnas.0534764100. Epub 2003 Mar 14. Proc Natl Acad Sci U S A. 2003. PMID: 12640143 Free PMC article.

6

Responsiveness to the retinoic acid receptor-selective retinoid LGD1550 correlates with abrogation of transforming growth factor alpha/epidermal growth factor receptor autocrine signaling in head and neck squamous carcinoma cells.

Lango M, Wentzel AL, Song JI, Xi S, Johnson DE, Lamph WW, Miller L, Grandis JR. Lango M, et al. Among authors: grandis jr. Clin Cancer Res. 2003 Sep 15;9(11):4205-13. Clin Cancer Res. 2003. PMID: 14519647

7

Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma.

Lai SY, Childs EE, Xi S, Coppelli FM, Gooding WE, Wells A, Ferris RL, Grandis JR. Lai SY, et al. Among authors: grandis jr. Oncogene. 2005 Jun 23;24(27):4442-9. doi: 10.1038/sj.onc.1208635. Oncogene. 2005. PMID: 15856028

8

STAT3 as a therapeutic target in head and neck cancer.

Leeman RJ, Lui VW, Grandis JR. Leeman RJ, et al. Among authors: grandis jr. Expert Opin Biol Ther. 2006 Mar;6(3):231-41. doi: 10.1517/14712598.6.3.231. Expert Opin Biol Ther. 2006. PMID: 16503733 Review.

9

Epidermal growth factor receptor biology in head and neck cancer.

Kalyankrishna S, Grandis JR. Kalyankrishna S, et al. Among authors: grandis jr. J Clin Oncol. 2006 Jun 10;24(17):2666-72. doi: 10.1200/JCO.2005.04.8306. J Clin Oncol. 2006. PMID: 16763281 Review.

10

Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1.

Lui VW, Boehm AL, Koppikar P, Leeman RJ, Johnson D, Ogagan M, Childs E, Freilino M, Grandis JR. Lui VW, et al. Among authors: grandis jr. Mol Pharmacol. 2007 May;71(5):1435-43. doi: 10.1124/mol.106.032284. Epub 2007 Feb 26. Mol Pharmacol. 2007. PMID: 17325127

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