Grandi F - Search Results

1

A dysfunctional TRPV4-GSK3β pathway prevents osteoarthritic chondrocytes from sensing changes in extracellular matrix viscoelasticity.

Agarwal P, Lee HP, Smeriglio P, Grandi F, Goodman S, Chaudhuri O, Bhutani N. Agarwal P, et al. Among authors: grandi f. Nat Biomed Eng. 2021 Dec;5(12):1472-1484. doi: 10.1038/s41551-021-00691-3. Epub 2021 Mar 11. Nat Biomed Eng. 2021. PMID: 33707778 Free PMC article.

2

Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation.

O'Donnell C, Migliore E, Grandi FC, Koltsov J, Lingampalli N, Cisar C, Indelli PF, Sebastiano V, Robinson WH, Bhutani N, Chu CR. O'Donnell C, et al. Among authors: grandi fc. J Orthop Res. 2019 Aug;37(8):1760-1770. doi: 10.1002/jor.24322. Epub 2019 May 29. J Orthop Res. 2019. PMID: 31042308 Free PMC article.

3

Single-cell mass cytometry reveals cross-talk between inflammation-dampening and inflammation-amplifying cells in osteoarthritic cartilage.

Grandi FC, Baskar R, Smeriglio P, Murkherjee S, Indelli PF, Amanatullah DF, Goodman S, Chu C, Bendall S, Bhutani N. Grandi FC, et al. Sci Adv. 2020 Mar 13;6(11):eaay5352. doi: 10.1126/sciadv.aay5352. eCollection 2020 Mar. Sci Adv. 2020. PMID: 32201724 Free PMC article.

4

Inhibition of TET1 prevents the development of osteoarthritis and reveals the 5hmC landscape that orchestrates pathogenesis.

Smeriglio P, Grandi FC, Davala S, Masarapu V, Indelli PF, Goodman SB, Bhutani N. Smeriglio P, et al. Sci Transl Med. 2020 Apr 15;12(539):eaax2332. doi: 10.1126/scitranslmed.aax2332. Sci Transl Med. 2020. PMID: 32295898

5

Epigenetic Therapies for Osteoarthritis.

Grandi FC, Bhutani N. Grandi FC, et al. Trends Pharmacol Sci. 2020 Aug;41(8):557-569. doi: 10.1016/j.tips.2020.05.008. Epub 2020 Jun 22. Trends Pharmacol Sci. 2020. PMID: 32586653 Free PMC article. Review.

6

Mapping 5-Hydroxymethylcytosine (5hmC) Modifications in Skeletal Tissues Using High-Throughput Sequencing.

Grandi FC, Bhutani N. Grandi FC, et al. Methods Mol Biol. 2021;2221:101-108. doi: 10.1007/978-1-0716-0989-7_8. Methods Mol Biol. 2021. PMID: 32979201

7

TET1 Directs Chondrogenic Differentiation by Regulating SOX9 Dependent Activation of Col2a1 and Acan In Vitro.

Smeriglio P, Grandi FC, Taylor SEB, Zalc A, Bhutani N. Smeriglio P, et al. JBMR Plus. 2020 Jun 26;4(8):e10383. doi: 10.1002/jbm4.10383. eCollection 2020 Aug. JBMR Plus. 2020. PMID: 33134768 Free PMC article.

8

Encapsulated Mesenchymal Stromal Cell Microbeads Promote Endogenous Regeneration of Osteoarthritic Cartilage Ex Vivo.

Sahu N, Agarwal P, Grandi F, Bruschi M, Goodman S, Amanatullah D, Bhutani N. Sahu N, et al. Among authors: grandi f. Adv Healthc Mater. 2021 Apr;10(8):e2002118. doi: 10.1002/adhm.202002118. Epub 2021 Jan 12. Adv Healthc Mater. 2021. PMID: 33434393 Free PMC article.

9

Single Cell Omics for Musculoskeletal Research.

Rai MF, Wu CL, Capellini TD, Guilak F, Dicks AR, Muthuirulan P, Grandi F, Bhutani N, Westendorf JJ. Rai MF, et al. Among authors: grandi f. Curr Osteoporos Rep. 2021 Apr;19(2):131-140. doi: 10.1007/s11914-021-00662-2. Epub 2021 Feb 9. Curr Osteoporos Rep. 2021. PMID: 33559841 Free PMC article. Review.

10

Preparation of Human Chondrocytes for Profiling Using Cytometry by Time-of-flight (cyTOF).

Grandi FC, Bhutani N. Grandi FC, et al. Bio Protoc. 2021 Jul 20;11(14):e4086. doi: 10.21769/BioProtoc.4086. eCollection 2021 Jul 20. Bio Protoc. 2021. PMID: 34395725 Free PMC article.

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