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EZH2 endorses cell plasticity to non-small cell lung cancer cells facilitating mesenchymal to epithelial transition and tumour colonization.
Gallardo A, Molina A, Asenjo HG, Lopez-Onieva L, Martorell-Marugán J, Espinosa-Martinez M, Griñan-Lison C, Alvarez-Perez JC, Cara FE, Navarro-Marchal SA, Carmona-Sáez P, Medina PP, Marchal JA, Granados-Principal S, Sánchez-Pozo A, Landeira D. Gallardo A, et al. Among authors: granados principal s. Oncogene. 2022 Jul;41(28):3611-3624. doi: 10.1038/s41388-022-02375-x. Epub 2022 Jun 9. Oncogene. 2022. PMID: 35680984
Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling.
González-González A, Muñoz-Muela E, Marchal JA, Cara FE, Molina MP, Cruz-Lozano M, Jiménez G, Verma A, Ramírez A, Qian W, Chen W, Kozielski AJ, Elemento O, Martín-Salvago MD, Luque RJ, Rosa-Garrido C, Landeira D, Quintana-Romero M, Rosato RR, García MA, Ramirez-Tortosa CL, Kim H, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Lorente JA, Sánchez-Rovira P, Chang JC, Granados-Principal S. González-González A, et al. Clin Cancer Res. 2018 Nov 15;24(22):5697-5709. doi: 10.1158/1078-0432.CCR-17-3125. Epub 2018 Jul 16. Clin Cancer Res. 2018. PMID: 30012564
Hydroxytyrosol inhibits cancer stem cells and the metastatic capacity of triple-negative breast cancer cell lines by the simultaneous targeting of epithelial-to-mesenchymal transition, Wnt/β-catenin and TGFβ signaling pathways.
Cruz-Lozano M, González-González A, Marchal JA, Muñoz-Muela E, Molina MP, Cara FE, Brown AM, García-Rivas G, Hernández-Brenes C, Lorente JA, Sanchez-Rovira P, Chang JC, Granados-Principal S. Cruz-Lozano M, et al. Eur J Nutr. 2019 Dec;58(8):3207-3219. doi: 10.1007/s00394-018-1864-1. Epub 2018 Nov 21. Eur J Nutr. 2019. PMID: 30460610
GARP is a key molecule for mesenchymal stromal cell responses to TGF-β and fundamental to control mitochondrial ROS levels.
Carrillo-Gálvez AB, Gálvez-Peisl S, González-Correa JE, de Haro-Carrillo M, Ayllón V, Carmona-Sáez P, Ramos-Mejía V, Galindo-Moreno P, Cara FE, Granados-Principal S, Muñoz P, Martin F, Anderson P. Carrillo-Gálvez AB, et al. Among authors: granados principal s. Stem Cells Transl Med. 2020 May;9(5):636-650. doi: 10.1002/sctm.19-0372. Epub 2020 Feb 19. Stem Cells Transl Med. 2020. PMID: 32073751 Free PMC article.
Antioxidants for the Treatment of Breast Cancer: Are We There Yet?
Griñan-Lison C, Blaya-Cánovas JL, López-Tejada A, Ávalos-Moreno M, Navarro-Ocón A, Cara FE, González-González A, Lorente JA, Marchal JA, Granados-Principal S. Griñan-Lison C, et al. Among authors: granados principal s. Antioxidants (Basel). 2021 Jan 31;10(2):205. doi: 10.3390/antiox10020205. Antioxidants (Basel). 2021. PMID: 33572626 Free PMC article. Review.
Nanomedicine as a Promising Tool to Overcome Immune Escape in Breast Cancer.
Navarro-Ocón A, Blaya-Cánovas JL, López-Tejada A, Blancas I, Sánchez-Martín RM, Garrido MJ, Griñán-Lisón C, Calahorra J, Cara FE, Ruiz-Cabello F, Marchal JA, Aptsiauri N, Granados-Principal S. Navarro-Ocón A, et al. Among authors: granados principal s. Pharmaceutics. 2022 Feb 25;14(3):505. doi: 10.3390/pharmaceutics14030505. Pharmaceutics. 2022. PMID: 35335881 Free PMC article. Review.
TGFβ Governs the Pleiotropic Activity of NDRG1 in Triple-Negative Breast Cancer Progression.
López-Tejada A, Griñán-Lisón C, González-González A, Cara FE, Luque RJ, Rosa-Garrido C, Blaya-Cánovas JL, Navarro-Ocón A, Valenzuela-Torres M, Parra-López M, Calahorra J, Blancas I, Marchal JA, Granados-Principal S. López-Tejada A, et al. Among authors: granados principal s. Int J Biol Sci. 2023 Jan 1;19(1):204-224. doi: 10.7150/ijbs.78738. eCollection 2023. Int J Biol Sci. 2023. PMID: 36594086 Free PMC article.
Drug Repurposing for Triple-Negative Breast Cancer.
Ávalos-Moreno M, López-Tejada A, Blaya-Cánovas JL, Cara-Lupiañez FE, González-González A, Lorente JA, Sánchez-Rovira P, Granados-Principal S. Ávalos-Moreno M, et al. Among authors: granados principal s. J Pers Med. 2020 Oct 29;10(4):200. doi: 10.3390/jpm10040200. J Pers Med. 2020. PMID: 33138097 Free PMC article. Review.
38 results