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rA1M-035, a Physicochemically Improved Human Recombinant α1-Microglobulin, Has Therapeutic Effects in Rhabdomyolysis-Induced Acute Kidney Injury.
Åkerström B, Rosenlöf L, Hägerwall A, Rutardottir S, Ahlstedt J, Johansson ME, Erlandsson L, Allhorn M, Gram M. Åkerström B, et al. Among authors: gram m. Antioxid Redox Signal. 2019 Feb 1;30(4):489-504. doi: 10.1089/ars.2017.7181. Epub 2018 Apr 11. Antioxid Redox Signal. 2019. PMID: 29471681 Free PMC article.
Protection of Kidney Function with Human Antioxidation Protein α1-Microglobulin in a Mouse 177Lu-DOTATATE Radiation Therapy Model.
Kristiansson A, Ahlstedt J, Holmqvist B, Brinte A, Tran TA, Forssell-Aronsson E, Strand SE, Gram M, Åkerström B. Kristiansson A, et al. Among authors: gram m. Antioxid Redox Signal. 2019 May 10;30(14):1746-1759. doi: 10.1089/ars.2018.7517. Epub 2018 Aug 14. Antioxid Redox Signal. 2019. PMID: 29943622 Free PMC article. Review.
The heme and radical scavenger α1-microglobulin (A1M) confers early protection of the immature brain following preterm intraventricular hemorrhage.
Romantsik O, Agyemang AA, Sveinsdóttir S, Rutardóttir S, Holmqvist B, Cinthio M, Mörgelin M, Gumus G, Karlsson H, Hansson SR, Åkerström B, Ley D, Gram M. Romantsik O, et al. Among authors: gram m. J Neuroinflammation. 2019 Jun 7;16(1):122. doi: 10.1186/s12974-019-1486-4. J Neuroinflammation. 2019. PMID: 31174551 Free PMC article.
Targeting elevated heme levels to treat a mouse model for Diamond-Blackfan Anemia.
Sjögren SE, Chen J, Mattebo A, Alattar AG, Karlsson H, Siva K, Soneji S, Tedgård U, Chen JJ, Gram M, Flygare J. Sjögren SE, et al. Among authors: gram m. Exp Hematol. 2022 Jan;105:50-61. doi: 10.1016/j.exphem.2021.10.005. Epub 2021 Oct 30. Exp Hematol. 2022. PMID: 34757171 Free PMC article.
Recombinant α1-Microglobulin (rA1M) Protects against Hematopoietic and Renal Toxicity, Alone and in Combination with Amino Acids, in a 177Lu-DOTATATE Mouse Radiation Model.
Alattar AG, Kristiansson A, Karlsson H, Vallius S, Ahlstedt J, Forssell-Aronsson E, Åkerström B, Strand SE, Flygare J, Gram M. Alattar AG, et al. Among authors: gram m. Biomolecules. 2023 Jun 1;13(6):928. doi: 10.3390/biom13060928. Biomolecules. 2023. PMID: 37371508 Free PMC article.
Characterization of choroid plexus in the preterm rabbit pup following subcutaneous administration of recombinant human IGF-1/IGFBP-3.
Ortenlöf N, Vallius S, Karlsson H, Ekström C, Kristiansson A, Holmqvist B, Göransson O, Vaváková M, Rydén M, Carey G, Barton N, Ley D, Gram M. Ortenlöf N, et al. Among authors: gram m. Fluids Barriers CNS. 2023 Aug 15;20(1):59. doi: 10.1186/s12987-023-00460-1. Fluids Barriers CNS. 2023. PMID: 37582792 Free PMC article.
153 results