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Page 1
Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo.
Laber S, Forcisi S, Bentley L, Petzold J, Moritz F, Smirnov KS, Al Sadat L, Williamson I, Strobel S, Agnew T, Sengupta S, Nicol T, Grallert H, Heier M, Honecker J, Mianne J, Teboul L, Dumbell R, Long H, Simon M, Lindgren C, Bickmore WA, Hauner H, Schmitt-Kopplin P, Claussnitzer M, Cox RD. Laber S, et al. Among authors: grallert h. Sci Adv. 2021 Jul 21;7(30):eabg0108. doi: 10.1126/sciadv.abg0108. Print 2021 Jul. Sci Adv. 2021. PMID: 34290091 Free PMC article.
Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA.
Holzapfel C, Grallert H, Huth C, Wahl S, Fischer B, Döring A, Rückert IM, Hinney A, Hebebrand J, Wichmann HE, Hauner H, Illig T, Heid IM. Holzapfel C, et al. Among authors: grallert h. Int J Obes (Lond). 2010 Oct;34(10):1538-45. doi: 10.1038/ijo.2010.79. Epub 2010 Apr 13. Int J Obes (Lond). 2010. PMID: 20386550 Free PMC article.
Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years.
Rzehak P, Scherag A, Grallert H, Sausenthaler S, Koletzko S, Bauer CP, Schaaf B, von Berg A, Berdel D, Borte M, Herbarth O, Krämer U, Illig T, Wichmann HE, Hebebrand J, Heinrich J; GINI and LISA Study Group. Rzehak P, et al. Among authors: grallert h. Obes Facts. 2010 Jun;3(3):173-80. doi: 10.1159/000314612. Epub 2010 May 28. Obes Facts. 2010. PMID: 20616607 Free PMC article.
First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study.
Holzapfel C, Grallert H, Baumert J, Thorand B, Döring A, Wichmann HE, Hauner H, Illig T, Mielck A. Holzapfel C, et al. Among authors: grallert h. J Epidemiol Community Health. 2011 Feb;65(2):174-6. doi: 10.1136/jech.2009.106492. Epub 2010 Jul 13. J Epidemiol Community Health. 2011. PMID: 20628085 Free PMC article.
Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146.
Then C, Wahl S, Kirchhofer A, Grallert H, Krug S, Kastenmüller G, Römisch-Margl W, Claussnitzer M, Illig T, Heier M, Meisinger C, Adamski J, Thorand B, Huth C, Peters A, Prehn C, Heukamp I, Laumen H, Lechner A, Hauner H, Seissler J. Then C, et al. Among authors: grallert h. PLoS One. 2013 Oct 24;8(10):e78430. doi: 10.1371/journal.pone.0078430. eCollection 2013. PLoS One. 2013. PMID: 24205231 Free PMC article.
Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.
Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B; DIAGRAM+Consortium; Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Claussnitzer M, et al. Among authors: grallert h. Cell. 2014 Jan 16;156(1-2):343-58. doi: 10.1016/j.cell.2013.10.058. Cell. 2014. PMID: 24439387 Free PMC article.
Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation.
Lee H, Qian K, von Toerne C, Hoerburger L, Claussnitzer M, Hoffmann C, Glunk V, Wahl S, Breier M, Eck F, Jafari L, Molnos S, Grallert H, Dahlman I, Arner P, Brunner C, Hauner H, Hauck SM, Laumen H. Lee H, et al. Among authors: grallert h. Nucleic Acids Res. 2017 Apr 7;45(6):3266-3279. doi: 10.1093/nar/gkx105. Nucleic Acids Res. 2017. PMID: 28334807 Free PMC article.
318 results