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CXCR2 inhibition enables NASH-HCC immunotherapy.
Leslie J, Mackey JBG, Jamieson T, Ramon-Gil E, Drake TM, Fercoq F, Clark W, Gilroy K, Hedley A, Nixon C, Luli S, Laszczewska M, Pinyol R, Esteban-Fabró R, Willoughby CE, Haber PK, Andreu-Oller C, Rahbari M, Fan C, Pfister D, Raman S, Wilson N, Müller M, Collins A, Geh D, Fuller A, McDonald D, Hulme G, Filby A, Cortes-Lavaud X, Mohamed NE, Ford CA, Raffo Iraolagoitia XL, McFarlane AJ, McCain MV, Ridgway RA, Roberts EW, Barry ST, Graham GJ, Heikenwälder M, Reeves HL, Llovet JM, Carlin LM, Bird TG, Sansom OJ, Mann DA. Leslie J, et al. Among authors: graham gj. Gut. 2022 Apr 27;71(10):2093-106. doi: 10.1136/gutjnl-2021-326259. Online ahead of print. Gut. 2022. PMID: 35477863 Free PMC article.
The chemokine receptor D6 limits the inflammatory response in vivo.
Jamieson T, Cook DN, Nibbs RJ, Rot A, Nixon C, McLean P, Alcami A, Lira SA, Wiekowski M, Graham GJ. Jamieson T, et al. Among authors: graham gj. Nat Immunol. 2005 Apr;6(4):403-11. doi: 10.1038/ni1182. Epub 2005 Mar 6. Nat Immunol. 2005. PMID: 15750596 Free article.
NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer.
Leung EYL, Ennis DP, Kennedy PR, Hansell C, Dowson S, Farquharson M, Spiliopoulou P, Nautiyal J, McNamara S, Carlin LM, Fisher K, Davis DM, Graham G, McNeish IA. Leung EYL, et al. Mol Ther Oncolytics. 2020 Feb 15;16:289-301. doi: 10.1016/j.omto.2020.02.001. eCollection 2020 Mar 27. Mol Ther Oncolytics. 2020. PMID: 32195317 Free PMC article.
Elevated expression of the chemokine-scavenging receptor D6 is associated with impaired lesion development in psoriasis.
Singh MD, King V, Baldwin H, Burden D, Thorrat A, Holmes S, McInnes IB, Nicoll R, Shams K, Pallas K, Jamieson T, Lee KM, Carballido JM, Rot A, Graham GJ. Singh MD, et al. Among authors: graham gj. Am J Pathol. 2012 Oct;181(4):1158-64. doi: 10.1016/j.ajpath.2012.06.042. Epub 2012 Aug 4. Am J Pathol. 2012. PMID: 22867710 Free PMC article.
CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells.
Sinclair A, Park L, Shah M, Drotar M, Calaminus S, Hopcroft LE, Kinstrie R, Guitart AV, Dunn K, Abraham SA, Sansom O, Michie AM, Machesky L, Kranc KR, Graham GJ, Pellicano F, Holyoake TL. Sinclair A, et al. Among authors: graham gj. Blood. 2016 Jul 21;128(3):371-83. doi: 10.1182/blood-2015-08-661785. Epub 2016 May 24. Blood. 2016. PMID: 27222476 Free PMC article.
163 results