Graham DK - Search Results

1

UNC5293, a potent, orally available and highly MERTK-selective inhibitor.

Zheng H, Zhao J, Li B, Zhang W, Stashko MA, Minson KA, Huey MG, Zhou Y, Earp HS, Kireev D, Graham DK, DeRyckere D, Frye SV, Wang X. Zheng H, et al. Among authors: graham dk. Eur J Med Chem. 2021 Aug 5;220:113534. doi: 10.1016/j.ejmech.2021.113534. Epub 2021 May 17. Eur J Med Chem. 2021. PMID: 34038857

2

Cloning and developmental expression analysis of the murine c-mer tyrosine kinase.

Graham DK, Bowman GW, Dawson TL, Stanford WL, Earp HS, Snodgrass HR. Graham DK, et al. Oncogene. 1995 Jun 15;10(12):2349-59. Oncogene. 1995. PMID: 7784083

3

Cloning and mRNA expression analysis of a novel human protooncogene, c-mer.

Graham DK, Dawson TL, Mullaney DL, Snodgrass HR, Earp HS. Graham DK, et al. Cell Growth Differ. 1994 Jun;5(6):647-57. Cell Growth Differ. 1994. PMID: 8086340

4

Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase.

Keating AK, Salzberg DB, Sather S, Liang X, Nickoloff S, Anwar A, Deryckere D, Hill K, Joung D, Sawczyn KK, Park J, Curran-Everett D, McGavran L, Meltesen L, Gore L, Johnson GL, Graham DK. Keating AK, et al. Among authors: graham dk. Oncogene. 2006 Oct 5;25(45):6092-100. doi: 10.1038/sj.onc.1209633. Epub 2006 May 1. Oncogene. 2006. PMID: 16652142

5

Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia.

Graham DK, Salzberg DB, Kurtzberg J, Sather S, Matsushima GK, Keating AK, Liang X, Lovell MA, Williams SA, Dawson TL, Schell MJ, Anwar AA, Snodgrass HR, Earp HS. Graham DK, et al. Clin Cancer Res. 2006 May 1;12(9):2662-9. doi: 10.1158/1078-0432.CCR-05-2208. Clin Cancer Res. 2006. PMID: 16675557

6

TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.

Linger RM, Keating AK, Earp HS, Graham DK. Linger RM, et al. Among authors: graham dk. Adv Cancer Res. 2008;100:35-83. doi: 10.1016/S0065-230X(08)00002-X. Adv Cancer Res. 2008. PMID: 18620092 Free PMC article. Review.

7

Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia.

Linger RM, DeRyckere D, Brandão L, Sawczyn KK, Jacobsen KM, Liang X, Keating AK, Graham DK. Linger RM, et al. Among authors: graham dk. Blood. 2009 Sep 24;114(13):2678-87. doi: 10.1182/blood-2009-03-209247. Epub 2009 Jul 30. Blood. 2009. PMID: 19643988 Free PMC article. Retracted.

8

Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors.

Linger RM, Keating AK, Earp HS, Graham DK. Linger RM, et al. Among authors: graham dk. Expert Opin Ther Targets. 2010 Oct;14(10):1073-90. doi: 10.1517/14728222.2010.515980. Expert Opin Ther Targets. 2010. PMID: 20809868 Free PMC article. Review.

9

Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus.

Migdall-Wilson J, Bates C, Schlegel J, Brandão L, Linger RM, DeRyckere D, Graham DK. Migdall-Wilson J, et al. Among authors: graham dk. PLoS One. 2012;7(2):e31635. doi: 10.1371/journal.pone.0031635. Epub 2012 Feb 20. PLoS One. 2012. PMID: 22363695 Free PMC article.

10

Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia.

Liu J, Yang C, Simpson C, Deryckere D, Van Deusen A, Miley MJ, Kireev D, Norris-Drouin J, Sather S, Hunter D, Korboukh VK, Patel HS, Janzen WP, Machius M, Johnson GL, Earp HS, Graham DK, Frye SV, Wang X. Liu J, et al. Among authors: graham dk. ACS Med Chem Lett. 2012 Feb 9;3(2):129-134. doi: 10.1021/ml200239k. ACS Med Chem Lett. 2012. PMID: 22662287 Free PMC article.

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