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Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation.
Mancini SJ, White AD, Bijland S, Rutherford C, Graham D, Richter EA, Viollet B, Touyz RM, Palmer TM, Salt IP. Mancini SJ, et al. Among authors: graham d. Mol Cell Endocrinol. 2017 Jan 15;440:44-56. doi: 10.1016/j.mce.2016.11.010. Epub 2016 Nov 11. Mol Cell Endocrinol. 2017. PMID: 27840174 Free PMC article.
Vascular Nox (NADPH Oxidase) Compartmentalization, Protein Hyperoxidation, and Endoplasmic Reticulum Stress Response in Hypertension.
Camargo LL, Harvey AP, Rios FJ, Tsiropoulou S, Da Silva RNO, Cao Z, Graham D, McMaster C, Burchmore RJ, Hartley RC, Bulleid N, Montezano AC, Touyz RM. Camargo LL, et al. Among authors: graham d. Hypertension. 2018 Jul;72(1):235-246. doi: 10.1161/HYPERTENSIONAHA.118.10824. Epub 2018 May 29. Hypertension. 2018. PMID: 29844144 Free PMC article.
NADPH Oxidase 5 Is a Pro-Contractile Nox Isoform and a Point of Cross-Talk for Calcium and Redox Signaling-Implications in Vascular Function.
Montezano AC, De Lucca Camargo L, Persson P, Rios FJ, Harvey AP, Anagnostopoulou A, Palacios R, Gandara ACP, Alves-Lopes R, Neves KB, Dulak-Lis M, Holterman CE, de Oliveira PL, Graham D, Kennedy C, Touyz RM. Montezano AC, et al. Among authors: graham d. J Am Heart Assoc. 2018 Jun 15;7(12):e009388. doi: 10.1161/JAHA.118.009388. J Am Heart Assoc. 2018. PMID: 29907654 Free PMC article.
Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension.
Alves-Lopes R, Montezano AC, Neves KB, Harvey A, Rios FJ, Skiba DS, Arendse LB, Guzik TJ, Graham D, Poglitsch M, Sturrock E, Touyz RM. Alves-Lopes R, et al. Among authors: graham d. Hypertension. 2021 Sep;78(3):604-616. doi: 10.1161/HYPERTENSIONAHA.121.17041. Epub 2021 Jul 26. Hypertension. 2021. PMID: 34304582 Free PMC article.
Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2.
Zoccarato A, Surdo NC, Aronsen JM, Fields LA, Mancuso L, Dodoni G, Stangherlin A, Livie C, Jiang H, Sin YY, Gesellchen F, Terrin A, Baillie GS, Nicklin SA, Graham D, Szabo-Fresnais N, Krall J, Vandeput F, Movsesian M, Furlan L, Corsetti V, Hamilton G, Lefkimmiatis K, Sjaastad I, Zaccolo M. Zoccarato A, et al. Among authors: graham d. Circ Res. 2015 Sep 25;117(8):707-19. doi: 10.1161/CIRCRESAHA.114.305892. Epub 2015 Aug 4. Circ Res. 2015. PMID: 26243800 Free article.
Congenic/consomic models of hypertension.
Graham D, McBride MW, Brain NJ, Dominiczak AF. Graham D, et al. Methods Mol Med. 2005;108:3-15. doi: 10.1385/1-59259-850-1:003. Methods Mol Med. 2005. PMID: 16028672
4,707 results