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Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies.
Benjamin R, Graham C, Yallop D, Jozwik A, Mirci-Danicar OC, Lucchini G, Pinner D, Jain N, Kantarjian H, Boissel N, Maus MV, Frigault MJ, Baruchel A, Mohty M, Gianella-Borradori A, Binlich F, Balandraud S, Vitry F, Thomas E, Philippe A, Fouliard S, Dupouy S, Marchiq I, Almena-Carrasco M, Ferry N, Arnould S, Konto C, Veys P, Qasim W; UCART19 Group. Benjamin R, et al. Among authors: graham c. Lancet. 2020 Dec 12;396(10266):1885-1894. doi: 10.1016/S0140-6736(20)32334-5. Lancet. 2020. PMID: 33308471 Clinical Trial.
Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma.
Graham CE, Jozwik A, Quartey-Papafio R, Ioannou N, Metelo AM, Scala C, Dickson G, Stewart O, Almena-Carrasco M, Peranzoni E, Ramsay AG, Patten PEM, Pertel T, Farzaneh F, Dupouy S, Pepper A, Benjamin R. Graham CE, et al. Leukemia. 2021 Dec;35(12):3581-3584. doi: 10.1038/s41375-021-01324-z. Epub 2021 Jun 18. Leukemia. 2021. PMID: 34145373 Free PMC article. No abstract available.
UCART19, a first-in-class allogeneic anti-CD19 chimeric antigen receptor T-cell therapy for adults with relapsed or refractory B-cell acute lymphoblastic leukaemia (CALM): a phase 1, dose-escalation trial.
Benjamin R, Jain N, Maus MV, Boissel N, Graham C, Jozwik A, Yallop D, Konopleva M, Frigault MJ, Teshima T, Kato K, Boucaud F, Balandraud S, Gianella-Borradori A, Binlich F, Marchiq I, Dupouy S, Almena-Carrasco M, Pannaux M, Fouliard S, Brissot E, Mohty M; CALM Study Group. Benjamin R, et al. Among authors: graham c. Lancet Haematol. 2022 Nov;9(11):e833-e843. doi: 10.1016/S2352-3026(22)00245-9. Epub 2022 Oct 10. Lancet Haematol. 2022. PMID: 36228643 Clinical Trial.
Four challenges to CAR T cells breaking the glass ceiling.
Bailey SR, Berger TR, Graham C, Larson RC, Maus MV. Bailey SR, et al. Among authors: graham c. Eur J Immunol. 2023 Nov;53(11):e2250039. doi: 10.1002/eji.202250039. Epub 2023 Jan 11. Eur J Immunol. 2023. PMID: 36585889 Review.
Macroevolution of the plant-hummingbird pollination system.
Barreto E, Boehm MMA, Ogutcen E, Abrahamczyk S, Kessler M, Bascompte J, Dellinger AS, Bello C, Dehling DM, Duchenne F, Kaehler M, Lagomarsino LP, Lohmann LG, Maglianesi MA, Morlon H, Muchhala N, Ornelas JF, Perret M, Salinas NR, Smith SD, Vamosi JC, Varassin IG, Graham CH. Barreto E, et al. Among authors: graham ch. Biol Rev Camb Philos Soc. 2024 May 5. doi: 10.1111/brv.13094. Online ahead of print. Biol Rev Camb Philos Soc. 2024. PMID: 38705863
Making informed choices on incorporating chemoprevention into carE (MiCHOICE, SWOG 1904): Design and methods of a cluster randomized controlled trial.
Crew KD, Anderson GL, Arnold KB, Stieb AP, Amenta JN, Collins N, Law CW, Pruthi S, Sandoval-Leon A, Bertoni D, Grosse Perdekamp MT, Colonna S, Krisher S, King T, Yee LD, Ballinger TJ, Braun-Inglis C, Mangino D, Wisinski KB, DeYoung CA, Ross M, Floyd J, Kaster A, Vander Walde L, Saphner T, Zarwan C, Lo S, Graham C, Conlin A, Yost K, Agnese D, Jernigan C, Hershman DL, Neuhouser ML, Arun B, Kukafka R. Crew KD, et al. Among authors: graham c. Contemp Clin Trials. 2024 May 2:107564. doi: 10.1016/j.cct.2024.107564. Online ahead of print. Contemp Clin Trials. 2024. PMID: 38704119
2,657 results