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A robust and highly efficient immune cell reprogramming system.
Bussmann LH, Schubert A, Vu Manh TP, De Andres L, Desbordes SC, Parra M, Zimmermann T, Rapino F, Rodriguez-Ubreva J, Ballestar E, Graf T. Bussmann LH, et al. Among authors: graf t. Cell Stem Cell. 2009 Nov 6;5(5):554-66. doi: 10.1016/j.stem.2009.10.004. Cell Stem Cell. 2009. PMID: 19896445 Free article.
HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.
Barneda-Zahonero B, Román-González L, Collazo O, Rafati H, Islam AB, Bussmann LH, di Tullio A, De Andres L, Graf T, López-Bigas N, Mahmoudi T, Parra M. Barneda-Zahonero B, et al. Among authors: graf t. PLoS Genet. 2013 May;9(5):e1003503. doi: 10.1371/journal.pgen.1003503. Epub 2013 May 16. PLoS Genet. 2013. PMID: 23696748 Free PMC article.
Musashi 2 in hematopoiesis.
de Andrés-Aguayo L, Varas F, Graf T. de Andrés-Aguayo L, et al. Among authors: graf t. Curr Opin Hematol. 2012 Jul;19(4):268-72. doi: 10.1097/MOH.0b013e328353c778. Curr Opin Hematol. 2012. PMID: 22517588 Review.
Hoxb5, a Trojan horse to generate T cells.
Stik G, Graf T. Stik G, et al. Among authors: graf t. Nat Immunol. 2018 Mar;19(3):210-212. doi: 10.1038/s41590-018-0053-y. Nat Immunol. 2018. PMID: 29476186 No abstract available.
Forcing cells to change lineages.
Graf T, Enver T. Graf T, et al. Nature. 2009 Dec 3;462(7273):587-94. doi: 10.1038/nature08533. Nature. 2009. PMID: 19956253 Review.
Zrf1 is required to establish and maintain neural progenitor identity.
Aloia L, Di Stefano B, Sessa A, Morey L, Santanach A, Gutierrez A, Cozzuto L, Benitah SA, Graf T, Broccoli V, Di Croce L. Aloia L, et al. Among authors: graf t. Genes Dev. 2014 Jan 15;28(2):182-97. doi: 10.1101/gad.228510.113. Genes Dev. 2014. PMID: 24449271 Free PMC article.
781 results