Graf M - Search Results

1

Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome.

Limbrick EM, Graf M, Derewacz DK, Nguyen F, Spraggins JM, Wieland M, Ynigez-Gutierrez AE, Reisman BJ, Zinshteyn B, McCulloch KM, Iverson TM, Green R, Wilson DN, Bachmann BO. Limbrick EM, et al. Among authors: graf m. J Am Chem Soc. 2020 Oct 28;142(43):18369-18377. doi: 10.1021/jacs.0c04675. Epub 2020 Oct 19. J Am Chem Soc. 2020. PMID: 32709196 Free PMC article.

2

The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex.

Seefeldt AC, Nguyen F, Antunes S, Pérébaskine N, Graf M, Arenz S, Inampudi KK, Douat C, Guichard G, Wilson DN, Innis CA. Seefeldt AC, et al. Among authors: graf m. Nat Struct Mol Biol. 2015 Jun;22(6):470-5. doi: 10.1038/nsmb.3034. Epub 2015 May 18. Nat Struct Mol Biol. 2015. PMID: 25984971

3

Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.

Seefeldt AC, Graf M, Pérébaskine N, Nguyen F, Arenz S, Mardirossian M, Scocchi M, Wilson DN, Innis CA. Seefeldt AC, et al. Among authors: graf m. Nucleic Acids Res. 2016 Mar 18;44(5):2429-38. doi: 10.1093/nar/gkv1545. Epub 2016 Jan 20. Nucleic Acids Res. 2016. PMID: 26792896 Free PMC article.

4

Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.

Arenz S, Juette MF, Graf M, Nguyen F, Huter P, Polikanov YS, Blanchard SC, Wilson DN. Arenz S, et al. Among authors: graf m. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7527-32. doi: 10.1073/pnas.1604790113. Epub 2016 Jun 21. Proc Natl Acad Sci U S A. 2016. PMID: 27330110 Free PMC article.

5

A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.

Arenz S, Bock LV, Graf M, Innis CA, Beckmann R, Grubmüller H, Vaiana AC, Wilson DN. Arenz S, et al. Among authors: graf m. Nat Commun. 2016 Jul 6;7:12026. doi: 10.1038/ncomms12026. Nat Commun. 2016. PMID: 27380950 Free PMC article.

6

Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions.

Graf M, Arenz S, Huter P, Dönhöfer A, Novácek J, Wilson DN. Graf M, et al. Nucleic Acids Res. 2017 Mar 17;45(5):2887-2896. doi: 10.1093/nar/gkw1272. Nucleic Acids Res. 2017. PMID: 27986857 Free PMC article.

7

Proline-rich antimicrobial peptides targeting protein synthesis.

Graf M, Mardirossian M, Nguyen F, Seefeldt AC, Guichard G, Scocchi M, Innis CA, Wilson DN. Graf M, et al. Nat Prod Rep. 2017 Jul 1;34(7):702-711. doi: 10.1039/c7np00020k. Epub 2017 May 24. Nat Prod Rep. 2017. PMID: 28537612 Free article. Review.

8

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.

Florin T, Maracci C, Graf M, Karki P, Klepacki D, Berninghausen O, Beckmann R, Vázquez-Laslop N, Wilson DN, Rodnina MV, Mankin AS. Florin T, et al. Among authors: graf m. Nat Struct Mol Biol. 2017 Sep;24(9):752-757. doi: 10.1038/nsmb.3439. Epub 2017 Jul 24. Nat Struct Mol Biol. 2017. PMID: 28741611 Free PMC article.

9

Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.

Huter P, Arenz S, Bock LV, Graf M, Frister JO, Heuer A, Peil L, Starosta AL, Wohlgemuth I, Peske F, Nováček J, Berninghausen O, Grubmüller H, Tenson T, Beckmann R, Rodnina MV, Vaiana AC, Wilson DN. Huter P, et al. Among authors: graf m. Mol Cell. 2017 Nov 2;68(3):515-527.e6. doi: 10.1016/j.molcel.2017.10.014. Mol Cell. 2017. PMID: 29100052 Free article.

10

Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.

Graf M, Huter P, Maracci C, Peterek M, Rodnina MV, Wilson DN. Graf M, et al. Nat Commun. 2018 Aug 3;9(1):3053. doi: 10.1038/s41467-018-05465-1. Nat Commun. 2018. PMID: 30076302 Free PMC article.

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