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New diterpenes from the marine sponge Spongionella sp. overcome drug resistance in prostate cancer by inhibition of P-glycoprotein.
Dyshlovoy SA, Shubina LK, Makarieva TN, Hauschild J, Strewinsky N, Guzii AG, Menshov AS, Popov RS, Grebnev BB, Busenbender T, Oh-Hohenhorst SJ, Maurer T, Tilki D, Graefen M, Bokemeyer C, Stonik VA, von Amsberg G. Dyshlovoy SA, et al. Among authors: graefen m. Sci Rep. 2022 Aug 9;12(1):13570. doi: 10.1038/s41598-022-17447-x. Sci Rep. 2022. PMID: 35945234 Free PMC article.
Chromosome 8p deletions and 8q gains are associated with tumor progression and poor prognosis in prostate cancer.
El Gammal AT, Brüchmann M, Zustin J, Isbarn H, Hellwinkel OJ, Köllermann J, Sauter G, Simon R, Wilczak W, Schwarz J, Bokemeyer C, Brümmendorf TH, Izbicki JR, Yekebas E, Fisch M, Huland H, Graefen M, Schlomm T. El Gammal AT, et al. Among authors: graefen m. Clin Cancer Res. 2010 Jan 1;16(1):56-64. doi: 10.1158/1078-0432.CCR-09-1423. Epub 2009 Dec 22. Clin Cancer Res. 2010. PMID: 20028754
Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer.
Minner S, Jessen B, Stiedenroth L, Burandt E, Köllermann J, Mirlacher M, Erbersdobler A, Eichelberg C, Fisch M, Brümmendorf TH, Bokemeyer C, Simon R, Steuber T, Graefen M, Huland H, Sauter G, Schlomm T. Minner S, et al. Among authors: graefen m. Clin Cancer Res. 2010 Mar 1;16(5):1553-60. doi: 10.1158/1078-0432.CCR-09-2546. Epub 2010 Feb 23. Clin Cancer Res. 2010. PMID: 20179235
ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.
Minner S, Enodien M, Sirma H, Luebke AM, Krohn A, Mayer PS, Simon R, Tennstedt P, Müller J, Scholz L, Brase JC, Liu AY, Schlüter H, Pantel K, Schumacher U, Bokemeyer C, Steuber T, Graefen M, Sauter G, Schlomm T. Minner S, et al. Among authors: graefen m. Clin Cancer Res. 2011 Sep 15;17(18):5878-88. doi: 10.1158/1078-0432.CCR-11-1251. Epub 2011 Jul 26. Clin Cancer Res. 2011. PMID: 21791629
Marked heterogeneity of ERG expression in large primary prostate cancers.
Minner S, Gärtner M, Freudenthaler F, Bauer M, Kluth M, Salomon G, Heinzer H, Graefen M, Bokemeyer C, Simon R, Sauter G, Schlomm T, Wilczak W. Minner S, et al. Among authors: graefen m. Mod Pathol. 2013 Jan;26(1):106-16. doi: 10.1038/modpathol.2012.130. Epub 2012 Aug 17. Mod Pathol. 2013. PMID: 22899295 Free article.
Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse.
Hennigs JK, Müller J, Adam M, Spin JM, Riedel E, Graefen M, Bokemeyer C, Sauter G, Huland H, Schlomm T, Minner S. Hennigs JK, et al. Among authors: graefen m. PLoS One. 2014 Jul 10;9(7):e100469. doi: 10.1371/journal.pone.0100469. eCollection 2014. PLoS One. 2014. PMID: 25010045 Free PMC article.
Additional androgen deprivation makes the difference: Biochemical recurrence-free survival in prostate cancer patients after HDR brachytherapy and external beam radiotherapy.
Schiffmann J, Lesmana H, Tennstedt P, Beyer B, Boehm K, Platz V, Tilki D, Salomon G, Petersen C, Krüll A, Graefen M, Schwarz R. Schiffmann J, et al. Among authors: graefen m. Strahlenther Onkol. 2015 Apr;191(4):330-7. doi: 10.1007/s00066-014-0794-y. Epub 2014 Dec 4. Strahlenther Onkol. 2015. PMID: 25471276 Clinical Trial.
923 results