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How do voltage-gated sodium channels enhance migration and invasiveness in cancer cells?
Biochim Biophys Acta. 2015 Oct;1848(10 Pt B):2493-501. doi: 10.1016/j.bbamem.2015.04.013. Epub 2015 Apr 25.
Biochim Biophys Acta. 2015.
PMID: 25922224
Free article.
Review.
SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer.
Bon E, Driffort V, Gradek F, Martinez-Caceres C, Anchelin M, Pelegrin P, Cayuela ML, Marionneau-Lambot S, Oullier T, Guibon R, Fromont G, Gutierrez-Pajares JL, Domingo I, Piver E, Moreau A, Burlaud-Gaillard J, Frank PG, Chevalier S, Besson P, Roger S.
Bon E, et al. Among authors: gradek f.
Nat Commun. 2016 Dec 5;7:13648. doi: 10.1038/ncomms13648.
Nat Commun. 2016.
PMID: 27917859
Free PMC article.
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Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.
Dutta S, Lopez Charcas O, Tanner S, Gradek F, Driffort V, Roger S, Selander K, Velu SE, Brouillette W.
Dutta S, et al. Among authors: gradek f.
Bioorg Med Chem. 2018 May 15;26(9):2428-2436. doi: 10.1016/j.bmc.2018.04.003. Epub 2018 Apr 3.
Bioorg Med Chem. 2018.
PMID: 29673714
Free PMC article.
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Sodium Channel Nav1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Cancer Cells Through its Regulation by the Salt-Inducible Kinase-1.
Gradek F, Lopez-Charcas O, Chadet S, Poisson L, Ouldamer L, Goupille C, Jourdan ML, Chevalier S, Moussata D, Besson P, Roger S.
Gradek F, et al.
Sci Rep. 2019 Dec 9;9(1):18652. doi: 10.1038/s41598-019-55197-5.
Sci Rep. 2019.
PMID: 31819138
Free PMC article.
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