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PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5'-Diphospho-glucuronosyltransferase Substrates.

Reddy MB, Bolger MB, Fraczkiewicz G, Del Frari L, Luo L, Lukacova V, Mitra A, Macwan JS, Mullin JM, Parrott N, Heikkinen AT. Reddy MB, et al. Among authors: fraczkiewicz g. Pharmaceutics. 2021 Aug 24;13(9):1325. doi: 10.3390/pharmaceutics13091325. Pharmaceutics. 2021. PMID: 34575401 Free PMC article. Review.

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Application of physiologically based biopharmaceutics modeling to understand the impact of dissolution differences on in vivo performance of immediate release products: The case of bisoprolol.

Macwan JS, Fraczkiewicz G, Bertolino M, Krüger P, Peters SA. Macwan JS, et al. Among authors: fraczkiewicz g. CPT Pharmacometrics Syst Pharmacol. 2021 Jun;10(6):622-632. doi: 10.1002/psp4.12634. Epub 2021 Jun 3. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34080804 Free PMC article.

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