Grütter MG - Search Results

1

Structure-based design of aliskiren, a novel orally effective renin inhibitor.

Wood JM, Maibaum J, Rahuel J, Grütter MG, Cohen NC, Rasetti V, Rüger H, Göschke R, Stutz S, Fuhrer W, Schilling W, Rigollier P, Yamaguchi Y, Cumin F, Baum HP, Schnell CR, Herold P, Mah R, Jensen C, O'Brien E, Stanton A, Bedigian MP. Wood JM, et al. Among authors: grutter mg. Biochem Biophys Res Commun. 2003 Sep 5;308(4):698-705. doi: 10.1016/s0006-291x(03)01451-7. Biochem Biophys Res Commun. 2003. PMID: 12927775

2

Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin.

Rahuel J, Rasetti V, Maibaum J, Rüeger H, Göschke R, Cohen NC, Stutz S, Cumin F, Fuhrer W, Wood JM, Grütter MG. Rahuel J, et al. Among authors: grutter mg. Chem Biol. 2000 Jul;7(7):493-504. doi: 10.1016/s1074-5521(00)00134-4. Chem Biol. 2000. PMID: 10903938

3

The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor.

Rahuel J, Priestle JP, Grütter MG. Rahuel J, et al. Among authors: grutter mg. J Struct Biol. 1991 Dec;107(3):227-36. doi: 10.1016/1047-8477(91)90048-2. J Struct Biol. 1991. PMID: 1807356

4

Active site binding loop stabilization in the subtilisin inhibitor eglin c: structural and functional studies on specifically designed mutants in complex with subtilisin and the uncomplexed inhibitor.

Hipler K, Priestle JP, Rahuel J, Grütter MG. Hipler K, et al. Among authors: grutter mg. Adv Exp Med Biol. 1996;379:43-7. doi: 10.1007/978-1-4613-0319-0_6. Adv Exp Med Biol. 1996. PMID: 8796309

5

Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms.

Priestle JP, Rahuel J, Rink H, Tones M, Grütter MG. Priestle JP, et al. Among authors: grutter mg. Protein Sci. 1993 Oct;2(10):1630-42. doi: 10.1002/pro.5560021009. Protein Sci. 1993. PMID: 8251938 Free PMC article.

6

Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.

Heinz DW, Priestle JP, Rahuel J, Wilson KS, Grütter MG. Heinz DW, et al. Among authors: grutter mg. J Mol Biol. 1991 Jan 20;217(2):353-71. doi: 10.1016/0022-2836(91)90549-l. J Mol Biol. 1991. PMID: 1992167

7

Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition.

Grütter MG, Priestle JP, Rahuel J, Grossenbacher H, Bode W, Hofsteenge J, Stone SR. Grütter MG, et al. EMBO J. 1990 Aug;9(8):2361-5. doi: 10.1002/j.1460-2075.1990.tb07410.x. EMBO J. 1990. PMID: 2369893 Free PMC article.

8

X-ray crystal structure of the serine proteinase inhibitor eglin c at 1.95 A resolution.

Hipler K, Priestle JP, Rahuel J, Grütter MG. Hipler K, et al. Among authors: grutter mg. FEBS Lett. 1992 Sep 7;309(2):139-45. doi: 10.1016/0014-5793(92)81082-w. FEBS Lett. 1992. PMID: 1505678 Free article.

9

Ligand-induced dimerization of the extracellular domain of the TGF-beta receptor type II.

Letourneur O, Goetschy JF, Horisberger M, Grütter MG. Letourneur O, et al. Among authors: grutter mg. Biochem Biophys Res Commun. 1996 Jul 25;224(3):709-16. doi: 10.1006/bbrc.1996.1088. Biochem Biophys Res Commun. 1996. PMID: 8713111

10

Generation of an antibody toolbox to characterize hERG.

Hausammann GJ, Heitkamp T, Matile H, Gsell B, Thoma R, Schmid G, Frasson D, Sievers M, Hennig M, Grütter MG. Hausammann GJ, et al. Among authors: grutter mg. Biochem Biophys Res Commun. 2013 Feb 1;431(1):70-5. doi: 10.1016/j.bbrc.2012.12.089. Epub 2012 Dec 28. Biochem Biophys Res Commun. 2013. PMID: 23277102

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

192 results

Search Page