Gräslund A - Search Results

1

Amino acid substitutions in human growth hormone affect secondary structure and receptor binding.

Rajkovic A, Kanchugal S, Abdurakhmanov E, Howard R, Wärmländer S, Erwin J, Barrera Saldaña HA, Gräslund A, Danielson H, Flores SC. Rajkovic A, et al. Among authors: graslund a. PLoS One. 2023 Mar 23;18(3):e0282741. doi: 10.1371/journal.pone.0282741. eCollection 2023. PLoS One. 2023. PMID: 36952491 Free PMC article.

2

Big dynorphin is a neuroprotector scaffold against amyloid β-peptide aggregation and cell toxicity.

Gallego-Villarejo L, Wallin C, Król S, Enrich-Bengoa J, Suades A, Aguilella-Arzo M, Gomara MJ, Haro I, Wärmlander S, Muñoz FJ, Gräslund A, Perálvarez-Marín A. Gallego-Villarejo L, et al. Among authors: graslund a. Comput Struct Biotechnol J. 2022 Oct 14;20:5672-5679. doi: 10.1016/j.csbj.2022.10.014. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 36284704 Free PMC article.

3

Choosing an Optimal Solvent Is Crucial for Obtaining Cell-Penetrating Peptide Nanoparticles with Desired Properties and High Activity in Nucleic Acid Delivery.

Biswas A, Maloverjan M, Padari K, Abroi A, Rätsep M, Wärmländer SKTS, Jarvet J, Gräslund A, Kisand V, Lõhmus R, Pooga M. Biswas A, et al. Among authors: graslund a. Pharmaceutics. 2023 Jan 24;15(2):396. doi: 10.3390/pharmaceutics15020396. Pharmaceutics. 2023. PMID: 36839718 Free PMC article.

4

Residue-specific binding of Ni(II) ions influences the structure and aggregation of amyloid beta (Aβ) peptides.

Berntsson E, Vosough F, Svantesson T, Pansieri J, Iashchishyn IA, Ostojić L, Dong X, Paul S, Jarvet J, Roos PM, Barth A, Morozova-Roche LA, Gräslund A, Wärmländer SKTS. Berntsson E, et al. Among authors: graslund a. Sci Rep. 2023 Feb 27;13(1):3341. doi: 10.1038/s41598-023-29901-5. Sci Rep. 2023. PMID: 36849796 Free PMC article.

5

Prion Protein Octarepeat Domain Forms Transient β-Sheet Structures upon Residue-Specific Binding to Cu(II) and Zn(II) Ions.

Gielnik M, Szymańska A, Dong X, Jarvet J, Svedružić ŽM, Gräslund A, Kozak M, Wärmländer SKTS. Gielnik M, et al. Among authors: graslund a. Biochemistry. 2023 Jun 6;62(11):1689-1705. doi: 10.1021/acs.biochem.3c00129. Epub 2023 May 10. Biochemistry. 2023. PMID: 37163663 Free PMC article.

6

Characterization of Uranyl (UO₂²⁺) Ion Binding to Amyloid Beta (Aβ) Peptides: Effects on Aβ Structure and Aggregation.

Berntsson E, Vosough F, Noormägi A, Padari K, Asplund F, Gielnik M, Paul S, Jarvet J, Tõugu V, Roos PM, Kozak M, Gräslund A, Barth A, Pooga M, Palumaa P, Wärmländer SKTS. Berntsson E, et al. Among authors: graslund a. ACS Chem Neurosci. 2023 Aug 2;14(15):2618-2633. doi: 10.1021/acschemneuro.3c00130. Epub 2023 Jul 24. ACS Chem Neurosci. 2023. PMID: 37487115 Free PMC article.

7

¹³C- and ¹⁵N-labeling of amyloid-β and inhibitory peptides to study their interaction via nanoscale infrared spectroscopy.

Paul S, Jeništová A, Vosough F, Berntsson E, Mörman C, Jarvet J, Gräslund A, Wärmländer SKTS, Barth A. Paul S, et al. Among authors: graslund a. Commun Chem. 2023 Aug 3;6(1):163. doi: 10.1038/s42004-023-00955-w. Commun Chem. 2023. PMID: 37537303 Free PMC article.

8

Erratum: The amyloid-inhibiting NCAM-PrP peptide targets Aβ peptide aggregation in membrane-mimetic environments.

Król S, Österlund N, Vosough F, Jarvet J, Wärmländer S, Barth A, Ilag LL, Magzoub M, Gräslund A, Mörman C. Król S, et al. Among authors: graslund a. iScience. 2023 Apr 9;26(4):106576. doi: 10.1016/j.isci.2023.106576. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091237 Free PMC article.

9

The C-terminal domain of the antiamyloid chaperone DNAJB6 binds to amyloid-β peptide fibrils and inhibits secondary nucleation.

Österlund N, Frankel R, Carlsson A, Thacker D, Karlsson M, Matus V, Gräslund A, Emanuelsson C, Linse S. Österlund N, et al. Among authors: graslund a. J Biol Chem. 2023 Nov;299(11):105317. doi: 10.1016/j.jbc.2023.105317. Epub 2023 Oct 4. J Biol Chem. 2023. PMID: 37797698 Free PMC article.

10

A Hairpin Motif in the Amyloid-β Peptide Is Important for Formation of Disease-Related Oligomers.

Khaled M, Rönnbäck I, Ilag LL, Gräslund A, Strodel B, Österlund N. Khaled M, et al. Among authors: graslund a. J Am Chem Soc. 2023 Aug 23;145(33):18340-18354. doi: 10.1021/jacs.3c03980. Epub 2023 Aug 9. J Am Chem Soc. 2023. PMID: 37555670 Free PMC article.

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