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Efficient asymmetric synthesis of P-chiral phosphine oxides via properly designed and activated benzoxazaphosphinine-2-oxide agents.
Han ZS, Goyal N, Herbage MA, Sieber JD, Qu B, Xu Y, Li Z, Reeves JT, Desrosiers JN, Ma S, Grinberg N, Lee H, Mangunuru HP, Zhang Y, Krishnamurthy D, Lu BZ, Song JJ, Wang G, Senanayake CH. Han ZS, et al. Among authors: goyal n. J Am Chem Soc. 2013 Feb 20;135(7):2474-7. doi: 10.1021/ja312352p. Epub 2013 Feb 6. J Am Chem Soc. 2013. PMID: 23369026
Design and synthesis of chiral oxathiozinone scaffolds: efficient synthesis of hindered enantiopure sulfinamides and sulfinyl ketimines.
Han ZS, Herbage MA, Mangunuru HP, Xu Y, Zhang L, Reeves JT, Sieber JD, Li Z, DeCroos P, Zhang Y, Li G, Li N, Ma S, Grinberg N, Wang X, Goyal N, Krishnamurthy D, Lu B, Song JJ, Wang G, Senanayake CH. Han ZS, et al. Among authors: goyal n. Angew Chem Int Ed Engl. 2013 Jun 24;52(26):6713-7. doi: 10.1002/anie.201301676. Epub 2013 May 15. Angew Chem Int Ed Engl. 2013. PMID: 23677810 No abstract available.
A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2.
Liu J, Pham PT, Skripnikova EV, Zheng S, Lovings LJ, Wang Y, Goyal N, Bellow SM, Mensah LM, Chatters AJ, Bratton MR, Wiese TE, Zhao M, Wang G, Foroozesh M. Liu J, et al. Among authors: goyal n. J Med Chem. 2015 Aug 27;58(16):6481-93. doi: 10.1021/acs.jmedchem.5b00494. Epub 2015 Aug 10. J Med Chem. 2015. PMID: 26222195 Free PMC article.
Identification of quinones as novel PIM1 kinase inhibitors.
Schroeder RL, Goyal N, Bratton M, Townley I, Pham NA, Tram P, Stone T, Geathers J, Nguyen K, Sridhar J. Schroeder RL, et al. Among authors: goyal n. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3187-3191. doi: 10.1016/j.bmcl.2016.04.079. Epub 2016 Apr 28. Bioorg Med Chem Lett. 2016. PMID: 27173800 Free PMC article.
Synthetic Method to Form 2,2'-Bis(naphthoquinone) Compounds.
Jha V, Goyal N, Stevens CK, Stevens E, Sridhar J. Jha V, et al. Among authors: goyal n. J Org Chem. 2017 Dec 15;82(24):13686-13692. doi: 10.1021/acs.joc.7b02501. Epub 2017 Nov 22. J Org Chem. 2017. PMID: 29111723
1,339 results