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High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells.
Chen JS, Chow RD, Song E, Mao T, Israelow B, Kamath K, Bozekowski J, Haynes WA, Filler RB, Menasche BL, Wei J, Alfajaro MM, Song W, Peng L, Carter L, Weinstein JS, Gowthaman U, Chen S, Craft J, Shon JC, Iwasaki A, Wilen CB, Eisenbarth SC. Chen JS, et al. Among authors: gowthaman u. Sci Immunol. 2022 Feb 4;7(68):eabl5652. doi: 10.1126/sciimmunol.abl5652. Epub 2022 Feb 4. Sci Immunol. 2022. PMID: 34914544 Free PMC article.
Regulation of IgE by T follicular helper cells.
Gowthaman U, Chen JS, Eisenbarth SC. Gowthaman U, et al. J Leukoc Biol. 2020 Mar;107(3):409-418. doi: 10.1002/JLB.3RI1219-425R. Epub 2020 Jan 22. J Leukoc Biol. 2020. PMID: 31965637 Free PMC article. Review.
Migratory CD11b+ conventional dendritic cells induce T follicular helper cell-dependent antibody responses.
Krishnaswamy JK, Gowthaman U, Zhang B, Mattsson J, Szeponik L, Liu D, Wu R, White T, Calabro S, Xu L, Collet MA, Yurieva M, Alsén S, Fogelstrand P, Walter A, Heath WR, Mueller SN, Yrlid U, Williams A, Eisenbarth SC. Krishnaswamy JK, et al. Among authors: gowthaman u. Sci Immunol. 2017 Dec 1;2(18):eaam9169. doi: 10.1126/sciimmunol.aam9169. Sci Immunol. 2017. PMID: 29196450 Free PMC article.
Identification of a T follicular helper cell subset that drives anaphylactic IgE.
Gowthaman U, Chen JS, Zhang B, Flynn WF, Lu Y, Song W, Joseph J, Gertie JA, Xu L, Collet MA, Grassmann JDS, Simoneau T, Chiang D, Berin MC, Craft JE, Weinstein JS, Williams A, Eisenbarth SC. Gowthaman U, et al. Science. 2019 Aug 30;365(6456):eaaw6433. doi: 10.1126/science.aaw6433. Epub 2019 Aug 1. Science. 2019. PMID: 31371561 Free PMC article.
Flow cytometric identification of Tfh13 cells in mouse and human.
Chen JS, Grassmann JDS, Gowthaman U, Olyha SJ, Simoneau T, Berin MC, Eisenbarth SC, Williams A. Chen JS, et al. Among authors: gowthaman u. J Allergy Clin Immunol. 2021 Feb;147(2):470-483. doi: 10.1016/j.jaci.2020.04.063. Epub 2020 Jul 21. J Allergy Clin Immunol. 2021. PMID: 32709424 Free PMC article. Review.
T follicular helper cells in IgE-mediated pathologies.
Gowthaman U, Sikder S, Lee D, Fisher C. Gowthaman U, et al. Curr Opin Immunol. 2022 Feb;74:133-139. doi: 10.1016/j.coi.2021.12.001. Epub 2021 Dec 21. Curr Opin Immunol. 2022. PMID: 34952257 Review.
Bridging channel dendritic cells induce immunity to transfused red blood cells.
Calabro S, Gallman A, Gowthaman U, Liu D, Chen P, Liu J, Krishnaswamy JK, Nascimento MS, Xu L, Patel SR, Williams A, Tormey CA, Hod EA, Spitalnik SL, Zimring JC, Hendrickson JE, Stowell SR, Eisenbarth SC. Calabro S, et al. Among authors: gowthaman u. J Exp Med. 2016 May 30;213(6):887-96. doi: 10.1084/jem.20151720. Epub 2016 May 16. J Exp Med. 2016. PMID: 27185856 Free PMC article.
IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection.
Liu D, Yin X, Olyha SJ, Nascimento MSL, Chen P, White T, Gowthaman U, Zhang T, Gertie JA, Zhang B, Xu L, Yurieva M, Devine L, Williams A, Eisenbarth SC. Liu D, et al. Among authors: gowthaman u. Immunity. 2019 Jul 16;51(1):64-76.e7. doi: 10.1016/j.immuni.2019.05.011. Epub 2019 Jun 20. Immunity. 2019. PMID: 31231033 Free PMC article.
32 results