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The potential anti-Alzheimer's activity of Oxalis corniculata Linn. Methanolic extract in experimental rats: Role of APOE4/LRP1, TLR4/NF-κβ/NLRP3, Wnt 3/β-catenin/GSK-3β, autophagy and apoptotic cues.
Abu-Elfotuh K, Hamdan AME, Mohamed SA, Bakr RO, Ahmed AH, Atwa AM, Hamdan AM, Alanzai AG, Alnahhas RK, Gowifel AMH, Salem MA. Abu-Elfotuh K, et al. Among authors: gowifel amh. J Ethnopharmacol. 2024 Apr 24;324:117731. doi: 10.1016/j.jep.2024.117731. Epub 2024 Jan 11. J Ethnopharmacol. 2024. PMID: 38218505 Free article.
A mechanistic exploration of the metabolome of African mango seeds and its potential to alleviate cognitive impairment induced by high-fat/high-carbohydrate diets: Involvement of PI3K/AKT/GSK-3β/CREB, PERK/CHOP/Bcl-2, and AMPK/SIRT-1/mTOR Axes.
Hassan YR, El-Shiekh RA, El Hefnawy HM, Mohamed OG, Abu-Elfotuh K, Hamdan AM, Darwish A, Gowifel AMH, Tripathi A, Michael CG. Hassan YR, et al. Among authors: gowifel amh. J Ethnopharmacol. 2024 Apr 24;324:117747. doi: 10.1016/j.jep.2024.117747. Epub 2024 Jan 11. J Ethnopharmacol. 2024. PMID: 38218500
Punicalagin's Protective Effects on Parkinson's Progression in Socially Isolated and Socialized Rats: Insights into Multifaceted Pathway.
Salem HA, Abu-Elfotuh K, Alzahrani S, Rizk NI, Ali HS, Elsherbiny N, Aljohani A, Hamdan AME, Chellasamy P, Abdou NS, Gowifel AMH, Darwish A, Ibrahim OM, Abd Elmageed ZY. Salem HA, et al. Among authors: gowifel amh. Pharmaceutics. 2023 Oct 4;15(10):2420. doi: 10.3390/pharmaceutics15102420. Pharmaceutics. 2023. PMID: 37896179 Free PMC article.
Anti-Alzheimer Activity of Combinations of Cocoa with Vinpocetine or Other Nutraceuticals in Rat Model: Modulation of Wnt3/β-Catenin/GSK-3β/Nrf2/HO-1 and PERK/CHOP/Bcl-2 Pathways.
Abu-Elfotuh K, Tolba AMA, Hussein FH, Hamdan AME, Rabeh MA, Alshahri SA, Ali AA, Mosaad SM, Mahmoud NA, Elsaeed MY, Abdelglil RM, El-Awady RR, Galal ERM, Kamal MM, Elsisi AMM, Darwish A, Gowifel AMH, Mahran YF. Abu-Elfotuh K, et al. Among authors: gowifel amh. Pharmaceutics. 2023 Jul 31;15(8):2063. doi: 10.3390/pharmaceutics15082063. Pharmaceutics. 2023. PMID: 37631278 Free PMC article.
The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways.
Abu-Elfotuh K, Selim HMRM, Riad OKM, Hamdan AME, Hassanin SO, Sharif AF, Moustafa NM, Gowifel AMH, Mohamed MYA, Atwa AM, Zaghlool SS, El-Din MN. Abu-Elfotuh K, et al. Among authors: gowifel amh. Front Pharmacol. 2023 Aug 2;14:1208252. doi: 10.3389/fphar.2023.1208252. eCollection 2023. Front Pharmacol. 2023. PMID: 37601053 Free PMC article.
Neuroprotective Effects of Some Nutraceuticals against Manganese-Induced Parkinson's Disease in Rats: Possible Modulatory Effects on TLR4/NLRP3/NF-κB, GSK-3β, Nrf2/HO-1, and Apoptotic Pathways.
Abu-Elfotuh K, Hamdan AME, Mohammed AA, Atwa AM, Kozman MR, Ibrahim AM, Motawea SM, Selim HMRM, Tohamy STK, Nour El-Din M, Zaghlool SS, Gowifel AMH, Awny MM. Abu-Elfotuh K, et al. Among authors: gowifel amh. Pharmaceuticals (Basel). 2022 Dec 14;15(12):1554. doi: 10.3390/ph15121554. Pharmaceuticals (Basel). 2022. PMID: 36559006 Free PMC article.