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Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.
Kotsiliti E, Leone V, Schuehle S, Govaere O, Li H, Wolf MJ, Horvatic H, Bierwirth S, Hundertmark J, Inverso D, Zizmare L, Sarusi-Portuguez A, Gupta R, O'Connor T, Giannou AD, Shiri AM, Schlesinger Y, Beccaria MG, Rennert C, Pfister D, Öllinger R, Gadjalova I, Ramadori P, Rahbari M, Rahbari N, Healy ME, Fernández-Vaquero M, Yahoo N, Janzen J, Singh I, Fan C, Liu X, Rau M, Feuchtenberger M, Schwaneck E, Wallace SJ, Cockell S, Wilson-Kanamori J, Ramachandran P, Kho C, Kendall TJ, Leblond AL, Keppler SJ, Bielecki P, Steiger K, Hofmann M, Rippe K, Zitzelsberger H, Weber A, Malek N, Luedde T, Vucur M, Augustin HG, Flavell R, Parnas O, Rad R, Pabst O, Henderson NC, Huber S, Macpherson A, Knolle P, Claassen M, Geier A, Trautwein C, Unger K, Elinav E, Waisman A, Abdullah Z, Haller D, Tacke F, Anstee QM, Heikenwalder M. Kotsiliti E, et al. Among authors: govaere o. J Hepatol. 2023 Aug;79(2):296-313. doi: 10.1016/j.jhep.2023.04.037. Epub 2023 May 22. J Hepatol. 2023. PMID: 37224925 Free PMC article.
The CCR2+ Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers.
Bartneck M, Schrammen PL, Möckel D, Govaere O, Liepelt A, Krenkel O, Ergen C, McCain MV, Eulberg D, Luedde T, Trautwein C, Kiessling F, Reeves H, Lammers T, Tacke F. Bartneck M, et al. Among authors: govaere o. Cell Mol Gastroenterol Hepatol. 2019;7(2):371-390. doi: 10.1016/j.jcmgh.2018.10.007. Epub 2018 Oct 18. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30704985 Free PMC article.
From NASH to HCC: current concepts and future challenges.
Anstee QM, Reeves HL, Kotsiliti E, Govaere O, Heikenwalder M. Anstee QM, et al. Among authors: govaere o. Nat Rev Gastroenterol Hepatol. 2019 Jul;16(7):411-428. doi: 10.1038/s41575-019-0145-7. Nat Rev Gastroenterol Hepatol. 2019. PMID: 31028350 Review.
Performance of the PRO-C3 collagen neo-epitope biomarker in non-alcoholic fatty liver disease.
Boyle M, Tiniakos D, Schattenberg JM, Ratziu V, Bugianessi E, Petta S, Oliveira CP, Govaere O, Younes R, McPherson S, Bedossa P, Nielsen MJ, Karsdal M, Leeming D, Kendrick S, Anstee QM. Boyle M, et al. Among authors: govaere o. JHEP Rep. 2019 Jul 4;1(3):188-198. doi: 10.1016/j.jhepr.2019.06.004. eCollection 2019 Sep. JHEP Rep. 2019. PMID: 32039369 Free PMC article.
Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort.
Anstee QM, Darlay R, Cockell S, Meroni M, Govaere O, Tiniakos D, Burt AD, Bedossa P, Palmer J, Liu YL, Aithal GP, Allison M, Yki-Järvinen H, Vacca M, Dufour JF, Invernizzi P, Prati D, Ekstedt M, Kechagias S, Francque S, Petta S, Bugianesi E, Clement K, Ratziu V, Schattenberg JM, Valenti L, Day CP, Cordell HJ, Daly AK; EPoS Consortium Investigators. Anstee QM, et al. Among authors: govaere o. J Hepatol. 2020 Sep;73(3):505-515. doi: 10.1016/j.jhep.2020.04.003. Epub 2020 Apr 13. J Hepatol. 2020. PMID: 32298765 Free article.
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis.
Govaere O, Cockell S, Tiniakos D, Queen R, Younes R, Vacca M, Alexander L, Ravaioli F, Palmer J, Petta S, Boursier J, Rosso C, Johnson K, Wonders K, Day CP, Ekstedt M, Orešič M, Darlay R, Cordell HJ, Marra F, Vidal-Puig A, Bedossa P, Schattenberg JM, Clément K, Allison M, Bugianesi E, Ratziu V, Daly AK, Anstee QM. Govaere O, et al. Sci Transl Med. 2020 Dec 2;12(572):eaba4448. doi: 10.1126/scitranslmed.aba4448. Sci Transl Med. 2020. PMID: 33268509 Free article.
75 results