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The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression.
Fougeray T, Polizzi A, Régnier M, Fougerat A, Ellero-Simatos S, Lippi Y, Smati S, Lasserre F, Tramunt B, Huillet M, Dopavogui L, Salvi J, Nédélec E, Gigot V, Smith L, Naylies C, Sommer C, Haas JT, Wahli W, Duez H, Gourdy P, Gamet-Payrastre L, Benani A, Burnol AF, Loiseau N, Postic C, Montagner A, Guillou H. Fougeray T, et al. Among authors: gourdy p. Cell Rep. 2022 Apr 12;39(2):110674. doi: 10.1016/j.celrep.2022.110674. Cell Rep. 2022. PMID: 35417722 Free article.
Selective Activation of Estrogen Receptor α Activation Function-1 Is Sufficient to Prevent Obesity, Steatosis, and Insulin Resistance in Mouse.
Guillaume M, Handgraaf S, Fabre A, Raymond-Letron I, Riant E, Montagner A, Vinel A, Buscato M, Smirnova N, Fontaine C, Guillou H, Arnal JF, Gourdy P. Guillaume M, et al. Among authors: gourdy p. Am J Pathol. 2017 Jun;187(6):1273-1287. doi: 10.1016/j.ajpath.2017.02.013. Epub 2017 May 11. Am J Pathol. 2017. PMID: 28502695 Free article.
Estrogen receptor subcellular localization and cardiometabolism.
Gourdy P, Guillaume M, Fontaine C, Adlanmerini M, Montagner A, Laurell H, Lenfant F, Arnal JF. Gourdy P, et al. Mol Metab. 2018 Sep;15:56-69. doi: 10.1016/j.molmet.2018.05.009. Epub 2018 May 16. Mol Metab. 2018. PMID: 29807870 Free PMC article. Review.
Hepatic PPARα is critical in the metabolic adaptation to sepsis.
Paumelle R, Haas JT, Hennuyer N, Baugé E, Deleye Y, Mesotten D, Langouche L, Vanhoutte J, Cudejko C, Wouters K, Hannou SA, Legry V, Lancel S, Lalloyer F, Polizzi A, Smati S, Gourdy P, Vallez E, Bouchaert E, Derudas B, Dehondt H, Gheeraert C, Fleury S, Tailleux A, Montagner A, Wahli W, Van Den Berghe G, Guillou H, Dombrowicz D, Staels B. Paumelle R, et al. Among authors: gourdy p. J Hepatol. 2019 May;70(5):963-973. doi: 10.1016/j.jhep.2018.12.037. Epub 2019 Jan 21. J Hepatol. 2019. PMID: 30677458 Free PMC article.
Regulation of hepatokine gene expression in response to fasting and feeding: Influence of PPAR-α and insulin-dependent signalling in hepatocytes.
Smati S, Régnier M, Fougeray T, Polizzi A, Fougerat A, Lasserre F, Lukowicz C, Tramunt B, Guillaume M, Burnol AF, Postic C, Wahli W, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: gourdy p. Diabetes Metab. 2020 Apr;46(2):129-136. doi: 10.1016/j.diabet.2019.05.005. Epub 2019 Jun 1. Diabetes Metab. 2020. PMID: 31163275
Selective Liver Estrogen Receptor α Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice.
Guillaume M, Riant E, Fabre A, Raymond-Letron I, Buscato M, Davezac M, Tramunt B, Montagner A, Smati S, Zahreddine R, Palierne G, Valera MC, Guillou H, Lenfant F, Unsicker K, Metivier R, Fontaine C, Arnal JF, Gourdy P. Guillaume M, et al. Among authors: gourdy p. Hepatol Commun. 2019 Apr 29;3(7):908-924. doi: 10.1002/hep4.1363. eCollection 2019 Jul. Hepatol Commun. 2019. PMID: 31304450 Free PMC article.
Sex differences in metabolic regulation and diabetes susceptibility.
Tramunt B, Smati S, Grandgeorge N, Lenfant F, Arnal JF, Montagner A, Gourdy P. Tramunt B, et al. Among authors: gourdy p. Diabetologia. 2020 Mar;63(3):453-461. doi: 10.1007/s00125-019-05040-3. Epub 2019 Nov 21. Diabetologia. 2020. PMID: 31754750 Free PMC article. Review.
Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor.
Lukowicz C, Ellero-Simatos S, Régnier M, Oliviero F, Lasserre F, Polizzi A, Montagner A, Smati S, Boudou F, Lenfant F, Guzylack-Pirou L, Menard S, Barretto S, Fougerat A, Lippi Y, Naylies C, Bertrand-Michel J, Belgnaoui AA, Theodorou V, Marchi N, Gourdy P, Gamet-Payrastre L, Loiseau N, Guillou H, Mselli-Lakhal L. Lukowicz C, et al. Among authors: gourdy p. Sci Rep. 2019 Dec 27;9(1):20169. doi: 10.1038/s41598-019-56570-0. Sci Rep. 2019. PMID: 31882815 Free PMC article.
Author Correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor.
Lukowicz C, Ellero-Simatos S, Régnier M, Oliviero F, Lasserre F, Polizzi A, Montagner A, Smati S, Boudou F, Lenfant F, Guzylack-Pirou L, Menard S, Barretto S, Fougerat A, Lippi Y, Naylies C, Bertrand-Michel J, Belgnaoui AA, Theodorou V, Marchi N, Gourdy P, Gamet-Payrastre L, Loiseau N, Guillou H, Mselli-Lakhal L. Lukowicz C, et al. Among authors: gourdy p. Sci Rep. 2020 Mar 3;10(1):4256. doi: 10.1038/s41598-020-61226-5. Sci Rep. 2020. PMID: 32123278 Free PMC article.
186 results