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Peptidic Connexin43 Therapeutics in Cardiac Reparative Medicine.
Marsh SR, Williams ZJ, Pridham KJ, Gourdie RG. Marsh SR, et al. Among authors: gourdie rg. J Cardiovasc Dev Dis. 2021 May 5;8(5):52. doi: 10.3390/jcdd8050052. J Cardiovasc Dev Dis. 2021. PMID: 34063001 Free PMC article. Review.
Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide.
Murphy SF, Varghese RT, Lamouille S, Guo S, Pridham KJ, Kanabur P, Osimani AM, Sharma S, Jourdan J, Rodgers CM, Simonds GR, Gourdie RG, Sheng Z. Murphy SF, et al. Among authors: gourdie rg. Cancer Res. 2016 Jan 1;76(1):139-49. doi: 10.1158/0008-5472.CAN-15-1286. Epub 2015 Nov 5. Cancer Res. 2016. PMID: 26542214 Free PMC article.
Connexin 43 confers chemoresistance through activating PI3K.
Pridham KJ, Shah F, Hutchings KR, Sheng KL, Guo S, Liu M, Kanabur P, Lamouille S, Lewis G, Morales M, Jourdan J, Grek CL, Ghatnekar GG, Varghese R, Kelly DF, Gourdie RG, Sheng Z. Pridham KJ, et al. Among authors: gourdie rg. Oncogenesis. 2022 Jan 12;11(1):2. doi: 10.1038/s41389-022-00378-7. Oncogenesis. 2022. PMID: 35022385 Free PMC article.
Tmem65 is critical for the structure and function of the intercalated discs in mouse hearts.
Teng ACT, Gu L, Di Paola M, Lakin R, Williams ZJ, Au A, Chen W, Callaghan NI, Zadeh FH, Zhou YQ, Fatah M, Chatterjee D, Jourdan LJ, Liu J, Simmons CA, Kislinger T, Yip CM, Backx PH, Gourdie RG, Hamilton RM, Gramolini AO. Teng ACT, et al. Among authors: gourdie rg. Nat Commun. 2022 Oct 18;13(1):6166. doi: 10.1038/s41467-022-33303-y. Nat Commun. 2022. PMID: 36257954 Free PMC article.
Mechanism of action of the anti-inflammatory connexin43 mimetic peptide JM2.
Rhett JM, Calder BW, Fann SA, Bainbridge H, Gourdie RG, Yost MJ. Rhett JM, et al. Among authors: gourdie rg. Am J Physiol Cell Physiol. 2017 Sep 1;313(3):C314-C326. doi: 10.1152/ajpcell.00229.2016. Epub 2017 Jul 12. Am J Physiol Cell Physiol. 2017. PMID: 28701358 Free PMC article.
Connexin 43-Based Therapeutics for Dermal Wound Healing.
Montgomery J, Ghatnekar GS, Grek CL, Moyer KE, Gourdie RG. Montgomery J, et al. Among authors: gourdie rg. Int J Mol Sci. 2018 Jun 15;19(6):1778. doi: 10.3390/ijms19061778. Int J Mol Sci. 2018. PMID: 29914066 Free PMC article. Review.
159 results