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Page 1
A human anti-matriptase-2 antibody limits iron overload, α-globin aggregates, and splenomegaly in β-thalassemic mice.
Wake M, Palin A, Belot A, Berger M, Lorgouilloux M, Bichon M, Papworth J, Bayliss L, Grimshaw B, Rynkiewicz N, Paterson J, Poindron A, Spearing E, Carter E, Hudson R, Campbell M, Petzer V, Besson-Fournier C, Latour C, Largounez A, Gourbeyre O, Fay A, Coppin H, Roth MP, Theurl I, Germaschewski V, Meynard D. Wake M, et al. Among authors: gourbeyre o. Blood Adv. 2024 Apr 23;8(8):1898-1907. doi: 10.1182/bloodadvances.2023012010. Blood Adv. 2024. PMID: 38241484 Free PMC article.
Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR.
Belot A, Gourbeyre O, Palin A, Rubio A, Largounez A, Besson-Fournier C, Latour C, Lorgouilloux M, Gallitz I, Montagner A, Polizzi A, Régnier M, Smati S, Zhang AS, Diaz-Munoz MD, Steinbicker AU, Guillou H, Roth MP, Coppin H, Meynard D. Belot A, et al. Among authors: gourbeyre o. Haematologica. 2021 Apr 1;106(4):1202-1206. doi: 10.3324/haematol.2019.237321. Haematologica. 2021. PMID: 32703788 Free PMC article. No abstract available.
LJ000328, a novel ALK2/3 kinase inhibitor, represses hepcidin and significantly improves the phenotype of IRIDA.
Belot A, Gourbeyre O, Fay A, Palin A, Besson-Fournier C, Latour C, Hopkins CR, Tidmarsh GF, Coppin H, Roth MP, Ritter MR, Hong CC, Meynard D. Belot A, et al. Among authors: gourbeyre o. Haematologica. 2020 Aug;105(8):e385-e388. doi: 10.3324/haematol.2019.236133. Epub 2019 Dec 5. Haematologica. 2020. PMID: 31806689 Free PMC article. No abstract available.
Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.
Nai A, Rubio A, Campanella A, Gourbeyre O, Artuso I, Bordini J, Gineste A, Latour C, Besson-Fournier C, Lin HY, Coppin H, Roth MP, Camaschella C, Silvestri L, Meynard D. Nai A, et al. Among authors: gourbeyre o. Blood. 2016 May 12;127(19):2327-36. doi: 10.1182/blood-2015-11-681494. Epub 2016 Jan 11. Blood. 2016. PMID: 26755707 Free PMC article.
Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.
Latour C, Besson-Fournier C, Meynard D, Silvestri L, Gourbeyre O, Aguilar-Martinez P, Schmidt PJ, Fleming MD, Roth MP, Coppin H. Latour C, et al. Among authors: gourbeyre o. Hepatology. 2016 Jan;63(1):126-37. doi: 10.1002/hep.28254. Epub 2015 Nov 12. Hepatology. 2016. PMID: 26406355
Proteomics of muscle chronological ageing in post-menopausal women.
Gueugneau M, Coudy-Gandilhon C, Gourbeyre O, Chambon C, Combaret L, Polge C, Taillandier D, Attaix D, Friguet B, Maier AB, Butler-Browne G, Béchet D. Gueugneau M, et al. Among authors: gourbeyre o. BMC Genomics. 2014 Dec 23;15:1165. doi: 10.1186/1471-2164-15-1165. BMC Genomics. 2014. PMID: 25532418 Free PMC article.
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