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Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension.
Rol N, de Raaf MA, Sun XQ, Kuiper VP, da Silva Gonçalves Bos D, Happé C, Kurakula K, Dickhoff C, Thuillet R, Tu L, Guignabert C, Schalij I, Lodder K, Pan X, Herrmann FE, van Nieuw Amerongen GP, Koolwijk P, Vonk-Noordegraaf A, de Man FS, Wollin L, Goumans MJ, Szulcek R, Bogaard HJ. Rol N, et al. Among authors: goumans mj. Cardiovasc Res. 2019 Feb 1;115(2):432-439. doi: 10.1093/cvr/cvy186. Cardiovasc Res. 2019. PMID: 30032282
The microRNA-15 family inhibits the TGFβ-pathway in the heart.
Tijsen AJ, van der Made I, van den Hoogenhof MM, Wijnen WJ, van Deel ED, de Groot NE, Alekseev S, Fluiter K, Schroen B, Goumans MJ, van der Velden J, Duncker DJ, Pinto YM, Creemers EE. Tijsen AJ, et al. Among authors: goumans mj. Cardiovasc Res. 2014 Oct 1;104(1):61-71. doi: 10.1093/cvr/cvu184. Epub 2014 Aug 7. Cardiovasc Res. 2014. PMID: 25103110
Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial Hypertension: A View on the Right Ventricle.
van der Bruggen CE, Happé CM, Dorfmüller P, Trip P, Spruijt OA, Rol N, Hoevenaars FP, Houweling AC, Girerd B, Marcus JT, Mercier O, Humbert M, Handoko ML, van der Velden J, Vonk Noordegraaf A, Bogaard HJ, Goumans MJ, de Man FS. van der Bruggen CE, et al. Among authors: goumans mj. Circulation. 2016 May 3;133(18):1747-60. doi: 10.1161/CIRCULATIONAHA.115.020696. Epub 2016 Mar 16. Circulation. 2016. PMID: 26984938
Response by van der Bruggen et al to Letter Regarding Article, "Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial Hypertension: A View on the Right Ventricle".
van der Bruggen CE, Happé CM, Goumans MJ, Bogaard HJ, Vonk Noordegraaf A, de Man FS. van der Bruggen CE, et al. Among authors: goumans mj. Circulation. 2016 Aug 30;134(9):e117-8. doi: 10.1161/CIRCULATIONAHA.116.024173. Circulation. 2016. PMID: 27572883 No abstract available.
286 results