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Cocaine perturbs mitovesicle biology in the brain.
D'Acunzo P, Ungania JM, Kim Y, Barreto BR, DeRosa S, Pawlik M, Canals-Baker S, Erdjument-Bromage H, Hashim A, Goulbourne CN, Neubert TA, Saito M, Sershen H, Levy E. D'Acunzo P, et al. Among authors: goulbourne cn. J Extracell Vesicles. 2023 Jan;12(1):e12301. doi: 10.1002/jev2.12301. J Extracell Vesicles. 2023. PMID: 36691887 Free PMC article.
Autophagy is a novel pathway for neurofilament protein degradation in vivo.
Rao MV, Darji S, Stavrides PH, Goulbourne CN, Kumar A, Yang DS, Yoo L, Peddy J, Lee JH, Yuan A, Nixon RA. Rao MV, et al. Among authors: goulbourne cn. Autophagy. 2023 Apr;19(4):1277-1292. doi: 10.1080/15548627.2022.2124500. Epub 2022 Sep 21. Autophagy. 2023. PMID: 36131358 Free PMC article.
Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency.
González BJ, Zhao H, Niu J, Williams DJ, Lee J, Goulbourne CN, Xing Y, Wang Y, Oberholzer J, Blumenkrantz MH, Chen X, LeDuc CA, Chung WK, Colecraft HM, Gromada J, Shen Y, Goland RS, Leibel RL, Egli D. González BJ, et al. Among authors: goulbourne cn. Commun Biol. 2022 Aug 2;5(1):779. doi: 10.1038/s42003-022-03696-z. Commun Biol. 2022. PMID: 35918471 Free PMC article.
Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques.
Lee JH, Yang DS, Goulbourne CN, Im E, Stavrides P, Pensalfini A, Chan H, Bouchet-Marquis C, Bleiwas C, Berg MJ, Huo C, Peddy J, Pawlik M, Levy E, Rao M, Staufenbiel M, Nixon RA. Lee JH, et al. Among authors: goulbourne cn. Nat Neurosci. 2022 Jun;25(6):688-701. doi: 10.1038/s41593-022-01084-8. Epub 2022 Jun 2. Nat Neurosci. 2022. PMID: 35654956 Free PMC article.
36 results