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Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells.
Planès R, Pinilla M, Santoni K, Hessel A, Passemar C, Lay K, Paillette P, Valadão AC, Robinson KS, Bastard P, Lam N, Fadrique R, Rossi I, Pericat D, Bagayoko S, Leon-Icaza SA, Rombouts Y, Perouzel E, Tiraby M; COVID Human Genetic Effort; Zhang Q, Cicuta P, Jouanguy E, Neyrolles O, Bryant CE, Floto AR, Goujon C, Lei FZ, Martin-Blondel G, Silva S, Casanova JL, Cougoule C, Reversade B, Marcoux J, Ravet E, Meunier E. Planès R, et al. Among authors: goujon c. Mol Cell. 2022 Jul 7;82(13):2385-2400.e9. doi: 10.1016/j.molcel.2022.04.033. Epub 2022 May 16. Mol Cell. 2022. PMID: 35594856 Free PMC article.
Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs.
Rebendenne A, Roy P, Bonaventure B, Chaves Valadão AL, Desmarets L, Arnaud-Arnould M, Rouillé Y, Tauziet M, Giovannini D, Touhami J, Lee Y, DeWeirdt P, Hegde M, Urbach S, Koulali KE, de Gracia FG, McKellar J, Dubuisson J, Wencker M, Belouzard S, Moncorgé O, Doench JG, Goujon C. Rebendenne A, et al. Among authors: goujon c. Nat Genet. 2022 Aug;54(8):1090-1102. doi: 10.1038/s41588-022-01110-2. Epub 2022 Jul 25. Nat Genet. 2022. PMID: 35879413
TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction.
Khan H, Winstone H, Jimenez-Guardeño JM, Graham C, Doores KJ, Goujon C, Matthews DA, Davidson AD, Rihn SJ, Palmarini M, Neil SJD, Malim MH. Khan H, et al. Among authors: goujon c. PLoS Pathog. 2021 Nov 22;17(11):e1009820. doi: 10.1371/journal.ppat.1009820. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34807954 Free PMC article.
Clash of the titans: interferons and SARS-CoV-2.
Jouvenet N, Goujon C, Banerjee A. Jouvenet N, et al. Among authors: goujon c. Trends Immunol. 2021 Dec;42(12):1069-1072. doi: 10.1016/j.it.2021.10.009. Epub 2021 Oct 16. Trends Immunol. 2021. PMID: 34742657 Free PMC article.
Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor.
Goujon C, Moncorgé O, Bauby H, Doyle T, Barclay WS, Malim MH. Goujon C, et al. J Virol. 2014 Aug;88(16):9017-26. doi: 10.1128/JVI.01269-14. Epub 2014 Jun 4. J Virol. 2014. PMID: 24899177 Free PMC article.
The myxovirus resistance 2 (MX2) protein of humans has been identified recently as an interferon (IFN)-inducible inhibitor of human immunodeficiency virus type 1 (HIV-1) that acts at a late postentry step of infection to prevent the nuclear accumulation of viral cDNA (C. …
The myxovirus resistance 2 (MX2) protein of humans has been identified recently as an interferon (IFN)-inducible inhibitor of human immunode …
The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry.
Doyle T, Moncorgé O, Bonaventure B, Pollpeter D, Lussignol M, Tauziet M, Apolonia L, Catanese MT, Goujon C, Malim MH. Doyle T, et al. Among authors: goujon c. Nat Microbiol. 2018 Dec;3(12):1369-1376. doi: 10.1038/s41564-018-0273-9. Epub 2018 Nov 26. Nat Microbiol. 2018. PMID: 30478388 Free PMC article.
Mammalian and Avian Host Cell Influenza A Restriction Factors.
McKellar J, Rebendenne A, Wencker M, Moncorgé O, Goujon C. McKellar J, et al. Among authors: goujon c. Viruses. 2021 Mar 22;13(3):522. doi: 10.3390/v13030522. Viruses. 2021. PMID: 33810083 Free PMC article. Review.
150 results