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Disruption of Glycogen Utilization Markedly Improves the Efficacy of Carboplatin against Preclinical Models of Clear Cell Ovarian Carcinoma.
Khan T, He Y, Kryza T, Harrington BS, Gunter JH, Sullivan MA, Cuda T, Rogers R, Davies CM, Broomfield A, Gough M, Wu AC, McGann T, Weroha SJ, Haluska P, Forbes JM, Armes JE, Barry SC, Coward JI, Jagasia N, Chetty N, Snell CE, Lourie R, Perrin LC, Hooper JD. Khan T, et al. Among authors: gough m. Cancers (Basel). 2020 Apr 3;12(4):869. doi: 10.3390/cancers12040869. Cancers (Basel). 2020. PMID: 32260077 Free PMC article.
Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma.
Kryza T, Khan T, Puttick S, Li C, Sokolowski KA, Tse BW, Cuda T, Lyons N, Gough M, Yin J, Parkin A, Deryugina EI, Quigley JP, Law RHP, Whisstock JC, Riddell AD, Barbour AP, Wyld DK, Thomas PA, Rose S, Snell CE, Pajic M, He Y, Hooper JD. Kryza T, et al. Among authors: gough m. Theranostics. 2020 Mar 4;10(9):4116-4133. doi: 10.7150/thno.43589. eCollection 2020. Theranostics. 2020. PMID: 32226543 Free PMC article.
Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian Cancer.
He Y, Khan T, Kryza T, Jones ML, Goh JB, Lyons NJ, Pearce LA, Lee MD, Gough M, Rogers R, Davies CM, Gilks CB, Hodgkinson T, Lourie R, Barry SC, Perrin LC, Williams CC, Puttick S, Adams TE, Munro TP, Hooper JD, Chetty N. He Y, et al. Among authors: gough m. Mol Pharm. 2021 Sep 6;18(9):3464-3474. doi: 10.1021/acs.molpharmaceut.1c00401. Epub 2021 Aug 27. Mol Pharm. 2021. PMID: 34448393
Preclinical Molecular PET-CT Imaging Targeting CDCP1 in Colorectal Cancer.
Cuda TJ, He Y, Kryza T, Khan T, Tse BW, Sokolowski KA, Liu C, Lyons N, Gough M, Snell CE, Wyld DK, Rose S, Riddell AD, Stevenson ARL, Thomas PA, Clark DA, Puttick S, Hooper JD. Cuda TJ, et al. Among authors: gough m. Contrast Media Mol Imaging. 2021 Sep 13;2021:3153278. doi: 10.1155/2021/3153278. eCollection 2021. Contrast Media Mol Imaging. 2021. PMID: 34621145 Free PMC article.
CUB Domain-Containing Protein 1 (CDCP1) is a rational target for the development of imaging tracers and antibody-drug conjugates for cancer detection and therapy.
Khan T, Lyons NJ, Gough M, Kwah KKX, Cuda TJ, Snell CE, Tse BW, Sokolowski KA, Pearce LA, Adams TE, Rose SE, Puttick S, Pajic M, Adams MN, He Y, Hooper JD, Kryza T. Khan T, et al. Among authors: gough m. Theranostics. 2022 Oct 3;12(16):6915-6930. doi: 10.7150/thno.78171. eCollection 2022. Theranostics. 2022. PMID: 36276654 Free PMC article.
Exploring the Potential of PEG-Heparin Hydrogels to Support Long-Term Ex Vivo Culture of Patient-Derived Breast Explant Tissues.
Koch MK, Ravichandran A, Murekatete B, Clegg J, Joseph MT, Hampson M, Jenkinson M, Bauer HS, Snell C, Liu C, Gough M, Thompson EW, Werner C, Hutmacher DW, Haupt LM, Bray LJ. Koch MK, et al. Among authors: gough m. Adv Healthc Mater. 2023 Jun;12(14):e2202202. doi: 10.1002/adhm.202202202. Epub 2023 Jan 4. Adv Healthc Mater. 2023. PMID: 36527735
GelMA, Click-Chemistry Gelatin and Bioprinted Polyethylene Glycol-Based Hydrogels as 3D Ex Vivo Drug Testing Platforms for Patient-Derived Breast Cancer Organoids.
Bock N, Forouz F, Hipwood L, Clegg J, Jeffery P, Gough M, van Wyngaard T, Pyke C, Adams MN, Bray LJ, Croft L, Thompson EW, Kryza T, Meinert C. Bock N, et al. Among authors: gough m. Pharmaceutics. 2023 Jan 12;15(1):261. doi: 10.3390/pharmaceutics15010261. Pharmaceutics. 2023. PMID: 36678890 Free PMC article.
553 results