Gough DJ - Search Results

1

Lineage-restricted neoplasia driven by Myc defaults to small cell lung cancer when combined with loss of p53 and Rb in the airway epithelium.

Chen J, Guanizo A, Luong Q, Jayasekara WSN, Jayasinghe D, Inampudi C, Szczepny A, Garama DJ, Russell PA, Ganju V, Cain JE, Watkins DN, Gough DJ. Chen J, et al. Among authors: gough dj. Oncogene. 2022 Jan;41(1):138-145. doi: 10.1038/s41388-021-02070-3. Epub 2021 Oct 21. Oncogene. 2022. PMID: 34675406

2

A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3.

Garama DJ, Harris TJ, White CL, Rossello FJ, Abdul-Hay M, Gough DJ, Levy DE. Garama DJ, et al. Among authors: gough dj. Mol Cell Biol. 2015 Nov;35(21):3646-56. doi: 10.1128/MCB.00541-15. Epub 2015 Aug 17. Mol Cell Biol. 2015. PMID: 26283727 Free PMC article.

3

Cre-dependent DNA recombination activates a STING-dependent innate immune response.

Pépin G, Ferrand J, Höning K, Jayasekara WS, Cain JE, Behlke MA, Gough DJ, G Williams BR, Hornung V, Gantier MP. Pépin G, et al. Among authors: gough dj. Nucleic Acids Res. 2016 Jun 20;44(11):5356-64. doi: 10.1093/nar/gkw405. Epub 2016 May 10. Nucleic Acids Res. 2016. PMID: 27166376 Free PMC article.

4

Mitochondrial STAT3: Powering up a potent factor.

Garama DJ, White CL, Balic JJ, Gough DJ. Garama DJ, et al. Among authors: gough dj. Cytokine. 2016 Nov;87:20-5. doi: 10.1016/j.cyto.2016.05.019. Epub 2016 Jun 3. Cytokine. 2016. PMID: 27269970 Review.

5

Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns.

Lee WT, Sun X, Tsai TS, Johnson JL, Gould JA, Garama DJ, Gough DJ, McKenzie M, Trounce IA, St John JC. Lee WT, et al. Among authors: gough dj. Cell Death Discov. 2017 Sep 11;3:17062. doi: 10.1038/cddiscovery.2017.62. eCollection 2017. Cell Death Discov. 2017. PMID: 28900542 Free PMC article.

6

A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer.

Alamgeer M, Neil Watkins D, Banakh I, Kumar B, Gough DJ, Markman B, Ganju V. Alamgeer M, et al. Among authors: gough dj. Invest New Drugs. 2018 Apr;36(2):288-298. doi: 10.1007/s10637-017-0555-8. Epub 2017 Dec 26. Invest New Drugs. 2018. PMID: 29277856 Clinical Trial.

7

The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.

Szczepny A, Carey K, McKenzie L, Jayasekara WSN, Rossello F, Gonzalez-Rajal A, McCaw AS, Popovski D, Wang D, Sadler AJ, Mahar A, Russell PA, Wright G, McCloy RA, Garama DJ, Gough DJ, Baylin SB, Burgess A, Cain JE, Watkins DN. Szczepny A, et al. Among authors: gough dj. Oncogene. 2018 Apr;37(14):1939-1948. doi: 10.1038/s41388-017-0022-1. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367758 Free PMC article.

8

Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine.

Sandow JJ, Rainczuk A, Infusini G, Makanji M, Bilandzic M, Wilson AL, Fairweather N, Stanton PG, Garama D, Gough D, Jobling TW, Webb AI, Stephens AN. Sandow JJ, et al. Proteomics Clin Appl. 2018 May;12(3):e1700135. doi: 10.1002/prca.201700135. Epub 2018 Mar 2. Proteomics Clin Appl. 2018. PMID: 29426060

9

STAT3: a multifaceted oncoprotein.

Guanizo AC, Fernando CD, Garama DJ, Gough DJ. Guanizo AC, et al. Among authors: gough dj. Growth Factors. 2018 Apr;36(1-2):1-14. doi: 10.1080/08977194.2018.1473393. Epub 2018 Jun 6. Growth Factors. 2018. PMID: 29873274 Review.

10

Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer.

Leong TL, Gayevskiy V, Steinfort DP, De Massy MR, Gonzalez-Rajal A, Marini KD, Stone E, Chin V, Havryk A, Plit M, Irving LB, Jennings BR, McCloy RA, Jayasekara WSN, Alamgeer M, Boolell V, Field A, Russell PA, Kumar B, Gough DJ, Szczepny A, Ganju V, Rossello FJ, Cain JE, Papenfuss AT, Asselin-Labat ML, Cowley MJ, Watkins DN. Leong TL, et al. Among authors: gough dj. Oncogene. 2019 Mar;38(10):1661-1675. doi: 10.1038/s41388-018-0536-1. Epub 2018 Oct 22. Oncogene. 2019. PMID: 30348992 Free PMC article.

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