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A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia.
Klein K, Kollmann S, Hiesinger A, List J, Kendler J, Klampfl T, Randhawa M, Trifinopoulos J, Maurer B, Grausenburger R, Bertram CA, Moriggl RH, Rülicke T, Mullighan CG, Witalisz-Siepracka A, Walter W, Hoermann G, Sexl V, Gotthardt D. Klein K, et al. Among authors: gotthardt d. Blood. 2024 Mar 18:blood.2023022655. doi: 10.1182/blood.2023022655. Online ahead of print. Blood. 2024. PMID: 38498036 Free article.
STATs in NK-Cells: The Good, the Bad, and the Ugly.
Gotthardt D, Sexl V. Gotthardt D, et al. Front Immunol. 2017 Jan 18;7:694. doi: 10.3389/fimmu.2016.00694. eCollection 2016. Front Immunol. 2017. PMID: 28149296 Free PMC article. Review.
NK Cell-Specific CDK8 Deletion Enhances Antitumor Responses.
Witalisz-Siepracka A, Gotthardt D, Prchal-Murphy M, Didara Z, Menzl I, Prinz D, Edlinger L, Putz EM, Sexl V. Witalisz-Siepracka A, et al. Among authors: gotthardt d. Cancer Immunol Res. 2018 Apr;6(4):458-466. doi: 10.1158/2326-6066.CIR-17-0183. Epub 2018 Jan 31. Cancer Immunol Res. 2018. PMID: 29386186
CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance.
Putz EM, Gotthardt D, Hoermann G, Csiszar A, Wirth S, Berger A, Straka E, Rigler D, Wallner B, Jamieson AM, Pickl WF, Zebedin-Brandl EM, Müller M, Decker T, Sexl V. Putz EM, et al. Among authors: gotthardt d. Cell Rep. 2013 Aug 15;4(3):437-44. doi: 10.1016/j.celrep.2013.07.012. Epub 2013 Aug 8. Cell Rep. 2013. PMID: 23933255 Free PMC article.
STAT1-S727 - the license to kill.
Putz EM, Gotthardt D, Sexl V. Putz EM, et al. Among authors: gotthardt d. Oncoimmunology. 2014 Dec 13;3(9):e955441. doi: 10.4161/21624011.2014.955441. eCollection 2014 Oct. Oncoimmunology. 2014. PMID: 25941617 Free PMC article.
190 results