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Optimization of the 2-arylquinazoline-4(3H)one scaffold for a selective and potent antitrypanosomal agent: modulation of the mechanism of action through chemical functionalization.
RSC Med Chem. 2023 Jul 11;14(10):1992-2006. doi: 10.1039/d3md00243h. eCollection 2023 Oct 18.
RSC Med Chem. 2023.
PMID: 37859724
Tautomerism and Rotamerism of Favipiravir and Halogenated Analogues in Solution and in the Solid State.
Romero AH, Fuentes G, Suescun L, Piro O, Echeverría G, Gotopo L, Pezaroglo H, Álvarez G, Cabrera G, Cerecetto H, Couto M.
Romero AH, et al. Among authors: gotopo l.
J Org Chem. 2023 Aug 4;88(15):10735-10752. doi: 10.1021/acs.joc.3c00777. Epub 2023 Jul 15.
J Org Chem. 2023.
PMID: 37452781
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Exploring binding chemistry of alkali/alkaline earth cations in solution through modulation of intramolecular charge-transfer in an excited ambidentate organic fluorophore.
Romero AH, Gotopo L, Cabrera G, Cerecetto H.
Romero AH, et al. Among authors: gotopo l.
Phys Chem Chem Phys. 2023 Jun 15;25(23):16030-16047. doi: 10.1039/d2cp04691a.
Phys Chem Chem Phys. 2023.
PMID: 37272652
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Synthesis and Antitrypanosomal and Mechanistic Studies of a Series of 2-Arylquinazolin-4-hydrazines: A Hydrazine Moiety as a Selective, Safe, and Specific Pharmacophore to Design Antitrypanosomal Agents Targeting NO Release.
Romero AH, Aguilera E, Gotopo L, Charris J, Rodríguez N, Oviedo H, Dávila B, Cabrera G, Cerecetto H.
Romero AH, et al. Among authors: gotopo l.
ACS Omega. 2022 Dec 6;7(50):47225-47238. doi: 10.1021/acsomega.2c06455. eCollection 2022 Dec 20.
ACS Omega. 2022.
PMID: 36570252
Free PMC article.
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Antimalarial Activity of Highly Coordinative Fused Heterocycles Targeting β-Hematin Crystallization.
Acosta ME, Gotopo L, Gamboa N, Rodrigues JR, Henriques GC, Cabrera G, Romero AH.
Acosta ME, et al. Among authors: gotopo l.
ACS Omega. 2022 Feb 25;7(9):7499-7514. doi: 10.1021/acsomega.1c05393. eCollection 2022 Mar 8.
ACS Omega. 2022.
PMID: 35284702
Free PMC article.
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Photo-Induced Partially Aromatized Intramolecular Charge Transfer.
Romero AH, Romero IE, Piro OE, Echeverría GA, Gotopo LA, Moller MN, Rodríguez GA, Cabrera GJ, Castro ER, López SE, Cerecetto HE.
Romero AH, et al. Among authors: gotopo la.
J Phys Chem B. 2021 Aug 19;125(32):9268-9285. doi: 10.1021/acs.jpcb.1c03747. Epub 2021 Aug 6.
J Phys Chem B. 2021.
PMID: 34357778
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