Gotfredsen CH - Search Results

1

Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery.

Solbak SMØ, Zang J, Narayanan D, Høj LJ, Bucciarelli S, Softley C, Meier S, Langkilde AE, Gotfredsen CH, Sattler M, Bach A. Solbak SMØ, et al. Among authors: gotfredsen ch. J Med Chem. 2020 Feb 13;63(3):1156-1177. doi: 10.1021/acs.jmedchem.9b01492. Epub 2020 Jan 23. J Med Chem. 2020. PMID: 31922756

2

Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles.

Maolanon AR, Villadsen JS, Christensen NJ, Hoeck C, Friis T, Harris P, Gotfredsen CH, Fristrup P, Olsen CA. Maolanon AR, et al. Among authors: gotfredsen ch. J Med Chem. 2014 Nov 26;57(22):9644-57. doi: 10.1021/jm501399d. Epub 2014 Nov 7. J Med Chem. 2014. PMID: 25380299

3

Fragment-Based Drug Discovery for RNA Targets.

Lundquist KP, Panchal V, Gotfredsen CH, Brenk R, Clausen MH. Lundquist KP, et al. Among authors: gotfredsen ch. ChemMedChem. 2021 Sep 6;16(17):2588-2603. doi: 10.1002/cmdc.202100324. Epub 2021 Aug 10. ChemMedChem. 2021. PMID: 34101375 Review.

4

Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening.

Lee SW, Tran KT, Vazquez-Uribe R, Gotfredsen CH, Clausen MH, Mendez BL, Montoya G, Bach A, Sommer MOA. Lee SW, et al. Among authors: gotfredsen ch. J Med Chem. 2022 Feb 24;65(4):3266-3305. doi: 10.1021/acs.jmedchem.1c01834. Epub 2022 Feb 10. J Med Chem. 2022. PMID: 35142491 Free article.

5

Small-molecule modulators of tumor necrosis factor signaling.

Chédotal H, Narayanan D, Povlsen K, Gotfredsen CH, Brambilla R, Gajhede M, Bach A, Clausen MH. Chédotal H, et al. Among authors: gotfredsen ch. Drug Discov Today. 2023 Jun;28(6):103575. doi: 10.1016/j.drudis.2023.103575. Epub 2023 Mar 30. Drug Discov Today. 2023. PMID: 37003513 Free article. Review.

6

Synthesis and properties of alpha- and beta-oligodeoxynucleotides containing alpha- and beta-1-(2-O-methyl-D-arabino-furanosyl)thymine.

Gotfredsen CH, Jacobsen JP, Wengel J. Gotfredsen CH, et al. Bioorg Med Chem. 1996 Aug;4(8):1217-25. doi: 10.1016/0968-0896(96)00117-4. Bioorg Med Chem. 1996. PMID: 8879543

7

A concise synthesis of castanospermine by the use of a transannular cyclization.

Jensen T, Mikkelsen M, Lauritsen A, Andresen TL, Gotfredsen CH, Madsen R. Jensen T, et al. Among authors: gotfredsen ch. J Org Chem. 2009 Nov 20;74(22):8886-9. doi: 10.1021/jo9019495. J Org Chem. 2009. PMID: 19856948

8

Structure-Activity Relationship Study Based on Autoinducing Peptide (AIP) from Dog Pathogen S. schleiferi.

Gless BH, Peng P, Pedersen KD, Gotfredsen CH, Ingmer H, Olsen CA. Gless BH, et al. Among authors: gotfredsen ch. Org Lett. 2017 Oct 6;19(19):5276-5279. doi: 10.1021/acs.orglett.7b02550. Epub 2017 Sep 27. Org Lett. 2017. PMID: 28952740

9

Bio-activity and dereplication-based discovery of ophiobolins and other fungal secondary metabolites targeting leukemia cells.

Bladt TT, Dürr C, Knudsen PB, Kildgaard S, Frisvad JC, Gotfredsen CH, Seiffert M, Larsen TO. Bladt TT, et al. Among authors: gotfredsen ch. Molecules. 2013 Nov 26;18(12):14629-50. doi: 10.3390/molecules181214629. Molecules. 2013. PMID: 24287995 Free PMC article.

10

Specific Electrostatic Molecular Recognition in Water.

Li M, Hoeck C, Schoffelen S, Gotfredsen CH, Meldal M. Li M, et al. Among authors: gotfredsen ch. Chemistry. 2016 May 17;22(21):7206-14. doi: 10.1002/chem.201600231. Epub 2016 Apr 13. Chemistry. 2016. PMID: 27073143

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