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Zika Virus: Origins, Pathological Action, and Treatment Strategies.
Gorshkov K, Shiryaev SA, Fertel S, Lin YW, Huang CT, Pinto A, Farhy C, Strongin AY, Zheng W, Terskikh AV. Gorshkov K, et al. Front Microbiol. 2019 Jan 7;9:3252. doi: 10.3389/fmicb.2018.03252. eCollection 2018. Front Microbiol. 2019. PMID: 30666246 Free PMC article. Review.
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.
Yang S, Xu M, Lee EM, Gorshkov K, Shiryaev SA, He S, Sun W, Cheng YS, Hu X, Tharappel AM, Lu B, Pinto A, Farhy C, Huang CT, Zhang Z, Zhu W, Wu Y, Zhou Y, Song G, Zhu H, Shamim K, Martínez-Romero C, García-Sastre A, Preston RA, Jayaweera DT, Huang R, Huang W, Xia M, Simeonov A, Ming G, Qiu X, Terskikh AV, Tang H, Song H, Zheng W. Yang S, et al. Among authors: gorshkov k. Cell Discov. 2018 Jun 5;4:31. doi: 10.1038/s41421-018-0034-1. eCollection 2018. Cell Discov. 2018. PMID: 29872540 Free PMC article.
Zika Virus-Induced Neuronal Apoptosis via Increased Mitochondrial Fragmentation.
Yang S, Gorshkov K, Lee EM, Xu M, Cheng YS, Sun N, Soheilian F, de Val N, Ming G, Song H, Tang H, Zheng W. Yang S, et al. Among authors: gorshkov k. Front Microbiol. 2020 Dec 23;11:598203. doi: 10.3389/fmicb.2020.598203. eCollection 2020. Front Microbiol. 2020. PMID: 33424801 Free PMC article.
Drug Discovery Strategies for SARS-CoV-2.
Shyr ZA, Gorshkov K, Chen CZ, Zheng W. Shyr ZA, et al. Among authors: gorshkov k. J Pharmacol Exp Ther. 2020 Oct;375(1):127-138. doi: 10.1124/jpet.120.000123. Epub 2020 Jul 28. J Pharmacol Exp Ther. 2020. PMID: 32723801 Free PMC article. Review.
Astrocytes as targets for drug discovery.
Gorshkov K, Aguisanda F, Thorne N, Zheng W. Gorshkov K, et al. Drug Discov Today. 2018 Mar;23(3):673-680. doi: 10.1016/j.drudis.2018.01.011. Epub 2018 Jan 6. Drug Discov Today. 2018. PMID: 29317338 Free PMC article. Review.
Advancing precision medicine with personalized drug screening.
Gorshkov K, Chen CZ, Marshall RE, Mihatov N, Choi Y, Nguyen DT, Southall N, Chen KG, Park JK, Zheng W. Gorshkov K, et al. Drug Discov Today. 2019 Jan;24(1):272-278. doi: 10.1016/j.drudis.2018.08.010. Epub 2018 Aug 17. Drug Discov Today. 2019. PMID: 30125678 Free PMC article. Review.
Induced pluripotent stem cells for neural drug discovery.
Farkhondeh A, Li R, Gorshkov K, Chen KG, Might M, Rodems S, Lo DC, Zheng W. Farkhondeh A, et al. Among authors: gorshkov k. Drug Discov Today. 2019 Apr;24(4):992-999. doi: 10.1016/j.drudis.2019.01.007. Epub 2019 Jan 18. Drug Discov Today. 2019. PMID: 30664937 Free PMC article. Review.
62 results