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Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa.
Ryan MD, Parkes AL, Corbett D, Dickie AP, Southey M, Andersen OA, Stein DB, Barbeau OR, Sanzone A, Thommes P, Barker J, Cain R, Compper C, Dejob M, Dorali A, Etheridge D, Evans S, Faulkner A, Gadouleau E, Gorman T, Haase D, Holbrow-Wilshaw M, Krulle T, Li X, Lumley C, Mertins B, Napier S, Odedra R, Papadopoulos K, Roumpelakis V, Spear K, Trimby E, Williams J, Zahn M, Keefe AD, Zhang Y, Soutter HT, Centrella PA, Clark MA, Cuozzo JW, Dumelin CE, Deng B, Hunt A, Sigel EA, Troast DM, DeJonge BLM. Ryan MD, et al. Among authors: gorman t. J Med Chem. 2021 Oct 14;64(19):14377-14425. doi: 10.1021/acs.jmedchem.1c00888. Epub 2021 Sep 27. J Med Chem. 2021. PMID: 34569791
C-H Cyanation of 6-Ring N-Containing Heteroaromatics.
Elbert BL, Farley AJM, Gorman TW, Johnson TC, Genicot C, Lallemand B, Pasau P, Flasz J, Castro JL, MacCoss M, Paton RS, Schofield CJ, Smith MD, Willis MC, Dixon DJ. Elbert BL, et al. Chemistry. 2017 Oct 20;23(59):14733-14737. doi: 10.1002/chem.201703931. Epub 2017 Sep 22. Chemistry. 2017. PMID: 28833674 Free PMC article.
Direct sulfonylation of anilines mediated by visible light.
Johnson TC, Elbert BL, Farley AJM, Gorman TW, Genicot C, Lallemand B, Pasau P, Flasz J, Castro JL, MacCoss M, Dixon DJ, Paton RS, Schofield CJ, Smith MD, Willis MC. Johnson TC, et al. Chem Sci. 2017 Nov 16;9(3):629-633. doi: 10.1039/c7sc03891g. eCollection 2018 Jan 21. Chem Sci. 2017. PMID: 29629128 Free PMC article.
Standardised quantitative assays for anti-SARS-CoV-2 immune response used in vaccine clinical trials by the CEPI Centralized Laboratory Network: a qualification analysis.
Manak M, Gagnon L, Phay-Tran S, Levesque-Damphousse P, Fabie A, Daugan M, Khan ST, Proud P, Hussey B, Knott D, Charlton S, Hallis B, Medigeshi GR, Garg N, Anantharaj A, Raqib R, Sarker P, Alam MM, Rahman M, Murreddu M, Balgobind A, Hofman R, Grappi S, Coluccio R, Calandro P, Montomoli E, Mattiuzzo G, Prior S, Le Duff Y, Page M, Mitchell J, Schwartz LM, Bartsch YC, Azizi A, Bernasconi V; CEPI CLN Study Group. Manak M, et al. Lancet Microbe. 2024 Mar;5(3):e216-e225. doi: 10.1016/S2666-5247(23)00324-5. Epub 2024 Jan 23. Lancet Microbe. 2024. PMID: 38278167 Free article.
121 results