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FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.
Brevini T, Maes M, Webb GJ, John BV, Fuchs CD, Buescher G, Wang L, Griffiths C, Brown ML, Scott WE 3rd, Pereyra-Gerber P, Gelson WTH, Brown S, Dillon S, Muraro D, Sharp J, Neary M, Box H, Tatham L, Stewart J, Curley P, Pertinez H, Forrest S, Mlcochova P, Varankar SS, Darvish-Damavandi M, Mulcahy VL, Kuc RE, Williams TL, Heslop JA, Rossetti D, Tysoe OC, Galanakis V, Vila-Gonzalez M, Crozier TWM, Bargehr J, Sinha S, Upponi SS, Fear C, Swift L, Saeb-Parsy K, Davies SE, Wester A, Hagström H, Melum E, Clements D, Humphreys P, Herriott J, Kijak E, Cox H, Bramwell C, Valentijn A, Illingworth CJR; UK-PBC Consortium; Dahman B, Bastaich DR, Ferreira RD, Marjot T, Barnes E, Moon AM, Barritt AS 4th, Gupta RK, Baker S, Davenport AP, Corbett G, Gorgoulis VG, Buczacki SJA, Lee JH, Matheson NJ, Trauner M, Fisher AJ, Gibbs P, Butler AJ, Watson CJE, Mells GF, Dougan G, Owen A, Lohse AW, Vallier L, Sampaziotis F. Brevini T, et al. Among authors: gorgoulis vg. Nature. 2023 Mar;615(7950):134-142. doi: 10.1038/s41586-022-05594-0. Epub 2022 Dec 5. Nature. 2023. PMID: 36470304 Free PMC article.
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.
Velimezi G, Liontos M, Vougas K, Roumeliotis T, Bartkova J, Sideridou M, Dereli-Oz A, Kocylowski M, Pateras IS, Evangelou K, Kotsinas A, Orsolic I, Bursac S, Cokaric-Brdovcak M, Zoumpourlis V, Kletsas D, Papafotiou G, Klinakis A, Volarevic S, Gu W, Bartek J, Halazonetis TD, Gorgoulis VG. Velimezi G, et al. Among authors: gorgoulis vg. Nat Cell Biol. 2013 Aug;15(8):967-77. doi: 10.1038/ncb2795. Epub 2013 Jul 14. Nat Cell Biol. 2013. PMID: 23851489
Apidima Cave fossils provide earliest evidence of Homo sapiens in Eurasia.
Harvati K, Röding C, Bosman AM, Karakostis FA, Grün R, Stringer C, Karkanas P, Thompson NC, Koutoulidis V, Moulopoulos LA, Gorgoulis VG, Kouloukoussa M. Harvati K, et al. Among authors: gorgoulis vg. Nature. 2019 Jul;571(7766):500-504. doi: 10.1038/s41586-019-1376-z. Epub 2019 Jul 10. Nature. 2019. PMID: 31292546
Cellular senescence as a source of SARS-CoV-2 quasispecies.
Karakasiliotis I, Lagopati N, Evangelou K, Gorgoulis VG. Karakasiliotis I, et al. Among authors: gorgoulis vg. FEBS J. 2023 Mar;290(5):1384-1392. doi: 10.1111/febs.16230. Epub 2021 Nov 8. FEBS J. 2023. PMID: 34653312 Free article. Review.
297 results