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Electron microscopy evidence that cytoplasmic localization of the p16(INK4A) "nuclear" cyclin-dependent kinase inhibitor (CKI) in tumor cells is specific and not an artifact. A study in non-small cell lung carcinomas.
Evangelou K, Bramis J, Peros I, Zacharatos P, Dasiou-Plakida D, Kalogeropoulos N, Asimacopoulos PJ, Kittas C, Marinos E, Gorgoulis VG. Evangelou K, et al. Among authors: gorgoulis vg. Biotech Histochem. 2004 Feb;79(1):5-10. doi: 10.1080/10520290310001659466. Biotech Histochem. 2004. PMID: 15223748
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior.
Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, Kotsinas A, Nahum O, Zoumpourlis V, Kouloukoussa M, Lygerou Z, Taraviras S, Kittas C, Bartkova J, Papavassiliou AG, Bartek J, Halazonetis TD, Gorgoulis VG. Liontos M, et al. Among authors: gorgoulis vg. Cancer Res. 2007 Nov 15;67(22):10899-909. doi: 10.1158/0008-5472.CAN-07-2837. Cancer Res. 2007. PMID: 18006835
351 results